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The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Oxidative stress and immune dysfunction are linked to both Hashimoto's thyroiditis and polycystic ovary syndrome, with diet and specific treatments important for managing these conditions.

The document concludes that respectful, gender-affirming healthcare improves mental health and encourages continued medical care for transgender and non-binary individuals.

Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.

The best long-lasting results in treating hair loss may be achieved through combination therapy, including treatments like finasteride, minoxidil, and platelet-rich plasma injections.

Adding bentonite clays to goat diets increased milk yield, periwinkle shell improved chicken egg production, and vaccination increased muscle area and carcass yield in calves.

HA-stimulated stem cell vesicles improved hair growth in male mice with androgenetic alopecia.

Minoxidil helps grow longer, thicker hair in bald scalps of stumptailed macaques, and early treatment is more effective.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Optimal long-acting finasteride injection dose found: 16.8 mg, effective for one month.

Finasteride microspheres help reduce hair loss for up to eight weeks with fewer side effects.

CB-03-01 is a promising skin cream for treating hormone-related skin problems without causing harmful body-wide effects.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

Dienogest combined with ethinylestradiol is a highly effective birth control that improves menstrual symptoms and has manageable side effects.

Finasteride reduces Hidradenitis Suppurativa flare-ups in children and teens, but long-term safety is unknown.

Metformin has limited effectiveness for improving PCOS symptoms and lacks clear benefits, needing more research to confirm its efficacy.

Women with regular menstrual cycles and PCOS have linked kisspeptin and LH hormone patterns, unlike those with irregular cycles.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Finasteride reduces male rat fertility by causing issues with copulatory plug formation.

The document concludes that there are various treatments for different types of alopecia, but more research is needed for evidence-based treatments.

The document concludes that proper diagnosis and combined treatments are key for hirsutism management, and weight loss may help overweight patients.

Hair transplantation surgery has improved, giving more natural results, and success depends on a skilled team and proper technique.

Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.

Laser hair removal is effective for dark hair but needs improvement for nonpigmented or fine hairs.

EF and PXE not closely related.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

Herbs like aloe vera and amla are effective and safe for treating hair loss.

Hair loss might be due to nerve issues, treatable with electric stimulation or acupuncture.

Hair transplantation is the best treatment for hair loss, with new technologies improving results, and stem cell and gene therapies may treat severe baldness in the future.