research Emerging Concepts About Prenatal Genesis, Aberrant Metabolism, and Treatment Paradigms in Polycystic Ovary Syndrome
PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.
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research International Society for the Study of Women's Sexual Health Clinical Practice Guideline for the Use of Systemic Testosterone for Hypoactive Sexual Desire Disorder in Women
Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.
research Alpha-Spinasterol from Melandrium Firmum Attenuates Benign Prostatic Hyperplasia in a Rat Model
α-spinasterol from Melandrium firmum can help reduce prostate enlargement.
research Two Transgender Men Receiving Subdermal Testosterone Pellets for Gender Affirmation
Testosterone pellets might work for transgender men's hormone therapy, but more research is needed.
research Endocrinology of Transgender Medicine
Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.
research Progress on the Road to Better Medical Care for Transgender Patients
The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.
research Treatment of Hirsutism with 5α-Reductase Inhibitors
New compounds may soon be tested to treat excessive hair growth in women.
research Evaluation of New Pregnane Derivatives as 5α-Reductase Inhibitors
New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.
research Cross-Sex Hormone Therapy for Gender Dysphoria
Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.
research Androgenic and Anti-Androgenic Effects of Progesterone Derivatives with Different Halogens as Substituents at the C-6 Position
Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.
research Synthesis and Pharmacological Evaluation of New 16-Methyl Pregnane Derivatives
New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.
research Medical Options for Care of Gender Diverse and Transgender Youth
Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.
research Finasteride
Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.
research Maintenance and Restoration of Growth in Thyroidectomized Rats
Thyroid hormone treatments help thyroidectomized rats grow normally.
research Androgen Insufficiency in Women: Diagnostic and Therapeutic Implications
Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.
research Androgen Treatment in Adolescent Males With Hypogonadism
Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.
research New and Consolidated Therapeutic Options for Pubertal Induction in Hypogonadism: In-Depth Review of the Literature
There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.
research Protective Effects of Melatonin Against Metabolic and Reproductive Disturbances in Polycystic Ovary Syndrome in Rats
Melatonin may help treat PCOS symptoms in rats.
research New 5α-Reductase Inhibitors: In Vitro and In Vivo Effects
Four new compounds were more effective than finasteride in treating prostate issues and hair loss, with one being 100 times more active and safe for use.
research Leydig Cell Hyperplasia and Adenomas in Mice Treated with Finasteride, a 5α-Reductase Inhibitor: A Possible Mechanism
High doses of finasteride cause cell growth and tumors in mice.
research Antiandrogen Therapy in Dermatology
Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.
research Clinical Applications of Antiandrogens
Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.
research The Role of the Adrenal Glands in Regulating Onset of Winter Fur Growth in Mink (Mustela Vison)
Adrenal glands delay the start of winter fur growth in mink.
research Biological Activity of Novel Progesterone Derivatives Having Bulky Ester Side Chains at C-3
The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.
research Hirsutism
Most women with excessive hair growth have PCOS; treatment varies and focuses on preventing new hair, with electrolysis as the only permanent removal method.
research Leydig Cell Hyperplasia and Adenomas in Mice Treated with Finasteride, a 5α-Reductase Inhibitor: A Possible Mechanism
Finasteride causes abnormal growth in male mice cells at high doses.
research The Effects of Estrogens on Linear Bone Growth
Oestrogens are key for bone growth during puberty in both boys and girls.
research Dermatologic Manifestations of Endocrine Disorders
Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.
research Female Pattern Hair Loss: A Review Article
Female pattern hair loss is common, linked to polycystic ovarian syndrome, and treated with topical Minoxidil.
research Gender-Affirming Hormone Therapy for Transgender Females
Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.