research New Intranasal and Injectable Gene Therapy for Healthy Life Extension
Gene therapy in mice increased lifespan and improved health without causing cancer.
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research Polycystic Ovary Syndrome
PCOS is a common condition in women that causes various symptoms and health issues, treatable with lifestyle changes and medication.
research A Simple Decision Tree for Identifying Early Oral Drug Candidates With Likely Pharmacokinetic Nonlinearity by Intestinal CYP3A Saturation
The decision tree can predict drug absorption issues with good accuracy but needs more validation and adjustments for other factors.
research A Modern View of Polycystic Ovarian Syndrome
The article concludes that better diagnosis and management of Polycystic Ovarian Syndrome are needed to improve women's health and prevent related diseases.
research Sertolioma in a Canadian Husky: Relationship Between Tumor, Hormones, Neurons, and Skin
Removing a testicular tumor in a dog reduced its aggressive behavior and skin problems.
research Frontal Fibrosing Alopecia: Clinical Features, Diagnosis, and Treatment Challenges
Frontal Fibrosing Alopecia is a type of hair loss affecting mostly older women, with no agreed best treatment.
research Effects of Altering Allopregnanolone Levels During Critical Neurodevelopmental Periods on Alcohol Consumption Vulnerability
Early NAS level changes affect alcohol consumption vulnerability.
research Randomized Split-Side Study Comparing Efficacy of Botulinum Toxin Type A Versus 0.9% Sodium Chloride in Scalp Psoriasis
Botulinum toxin type A significantly reduces scalp psoriasis severity compared to placebo.
research In-Silico Study of Bioactive Compounds of Natural Materials as a JAK-Signal Transducer and Activator of Transcription Inhibitor for Anti-Alopecia
Three compounds from Dadap leaves may help treat hair loss.
research Comparison of Androgenic Hormone Levels in Various Phenotypes of Polycystic Ovarian Syndrome in High School Girls Aged 14 to 18 Years
Girls with PCOS and menstrual disorders have notably higher androgen hormone levels.
research Cicatricial Alopecia: What's New in Etiology?
Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.
research Androgen Effects on the Skin
Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.
research Comparative Study of Efficacy of Excimer Light Therapy vs Intralesional Triamcinolone vs Topical 5% Minoxidil: An Observational Study
Intralesional triamcinolone is the most effective treatment for hair regrowth in alopecia areata patients.
research Alopecias
The document concludes that non-scarring alopecias can be reversed, but scarring alopecias cause permanent hair loss.
research Gonads
The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.
research Study of Therapeutic Comparison of Tacrolimus 0.1% and Minoxidil 2% in Alopecia Areata
Minoxidil 2% is more effective than tacrolimus 0.1% for hair regrowth in mild to moderate patchy hair loss, and combining both might give better results.
research Dialogues in Dermatology: Highlights from 2011
2011 dermatology discussions highlighted stem cell hair treatments, new lichen planopilaris therapies, skin side effects from cancer drugs, emerging allergens, and the link between food allergies and skin issues.
research Regenerative Medicine of Epidermal Structures
New treatments for skin and hair repair show promise, but further improvements are needed.
research Innovations in Chemotherapy and Radiation Therapy: Implications and Opportunities for the Asia-Pacific Rim
New cancer treatments are more precise and less toxic, improving survival rates, but Asia faces challenges in adopting these advancements.
research The Ability of Melatonin to Influence Oxidative Stress and Lower the Dose of Prednisolone in Patients with Alopecia Areata
Melatonin may help reduce the needed dose of prednisolone and improve hair growth in alopecia areata patients.
research Cytostatics and Immunosuppressive Drugs: Toxicities and Management
Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.
research Toxicity of the Pharmaceuticals Finasteride and Melengestrol Acetate to Benthic Invertebrates
Finasteride harms invertebrates' survival and burial ability.
research Finasteride
Finasteride helps hair growth and prostate issues but may cause sexual side effects and increase tumor risk.
research Limitations of Trichoscopy in Diagnosing Telogen Effluvium
Trichoscopy is not specific for diagnosing telogen effluvium and both telogen effluvium and androgenetic alopecia often occur together.
research Cannabinoid Compounds as a Pharmacotherapeutic Option for the Treatment of Non-Cancer Skin Diseases
Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.
research Frontal Fibrosing Alopecia: An Update on the Hypothesis of Pathogenesis and Treatment
The document concluded that more research is needed to find the best treatment for Frontal fibrosing alopecia.
research Identification of Sirtuin 1 as a Promising Therapeutic Target for Hypertrophic Scars
Sirtuin 1 could be a potential drug target for treating hypertrophic scars.
research Structural Mechanism of TRPV3 Channel Inhibition by the Plant-Derived Coumarin Osthole
Osthole inhibits the TRPV3 channel by binding to specific sites, potentially aiding drug development for skin diseases and cancers.
research Treatment of Hirsutism with Flutamide and a Low-Dosage Oral Contraceptive in Polycystic Ovarian Disease Patients
Flutamide combined with a low-dose birth control pill effectively reduces excessive hair growth in women with polycystic ovarian disease.
research Mechanism of Action of Bolandiol (19-Nortestosterone-3β,17β-Diol), a Unique Anabolic Steroid with Androgenic, Estrogenic, and Progestational Activities
Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.