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This study found that treatment with vitamin D increased the expression of LL-37 through the vitamin D receptor in cultured sebocytes.

This research suggests that the vitamin D receptor may regulate hair follicle cycling and provide genoprotection against skin carcinogenesis through a mechanism independent of 1,25-dihydroxyvitamin D3, based on evidence from mouse models.

A genetic mutation caused severe rickets and alopecia in an Indian patient, but high-dose calcium and phosphate treatment improved their condition.

This study demonstrated that both HR isoforms are expressed in keratinocytes, but HRDelta1072-1126 lacks corepressor activity and may act as a coactivator by inhibiting HDAC recruitment to the VDR transcriptional complex.

This study suggests that vitamin D-upregulated protein 1 (VDUP1) might play a unique role in regulating the differentiation of epidermal cells.

This study found that women with PCOS had higher levels of Nesfatin-1 and lower levels of vitamin D, which may be linked to increased blood pressure and potential hypertension.

This study found that 1,25 dihydroxyvitamin D3 significantly increased the expression and activity of vasculoprotective natriuretic peptide receptor-A in cultured inner medullary collecting duct cells, suggesting a potential mechanistic role in cardiovascular and renal benefits.

This review discusses the relationship between vitamin D and various skin diseases but reports no new clinical results, emphasizing the need to assess and correct vitamin D deficiencies.

Vitamin D deficiency is common in women with PCOS and linked to some metabolic problems, but not the main cause of their metabolic issues.

This study found that VDR deficiency in mice leads to various skin pathologies but does not affect the phenotype or function of Langerhans cells.

This review discusses how vitamin D and calcium signaling are essential for wound healing by activating epidermal and hair follicle stem cells, noting that deficiencies may lead to delayed or chronic wounds.

This study found that vitamin D receptor expression is associated with proliferating keratinocytes, while retinoid X receptor α is linked to differentiating keratinocytes, suggesting differential targeting by vitamin D metabolites.

This review discusses vitamin D's role in hair follicle biology and its association with hair loss but reports no conclusive evidence for its effectiveness as a treatment, indicating the need for further studies.

This review examines the potential roles of vitamin D in the pathogenesis of alopecia areata and suggests that vitamin D analogs like calcipotriol may have therapeutic potential.

This review discusses the role of vitamin D metabolism in skin immunity and wound healing but does not present new results, highlighting the need for further research into its therapeutic applications.

This study demonstrated that hyaluronan gel is a promising biomaterial for 3-D in vitro culture of mouse ovarian follicles, supporting the production of fertilizable metaphase II oocytes.

This review discusses vitamin D and calcium signaling roles in epidermal stem cell processes essential for wound healing but reports no new experimental results, emphasizing their potential interdependent regulatory mechanisms.

This review discusses the relationship between vitamin D and various skin diseases, highlighting recent findings on its role and the importance of assessing and correcting vitamin D levels, but reports no new clinical results.

This study found that 64.8% of patients with different types of alopecia had vitamin D deficiency, and those with lichen planopilaris and telogen effluvium had higher odds of severe deficiency compared to patients with alopecia areata.

This study found that patients with alopecia areata had significantly lower serum levels of 25-hydroxy vitamin D compared to control subjects.

In this study, researchers observed that the absence of the vitamin D receptor or its ligand-activated transcription in mice did not affect glucose homeostasis or gene expression in islets.

This study found that the vitamin D receptor, but not its ligand, regulates genes involved in hair cycle progression, suggesting a role in integrating hormone signaling pathways for hair and epidermal functions.

This review discusses the potential role of vitamin D deficiency in cardiovascular and renal diseases and suggests that supplemental vitamin D could benefit cardiovascular outcomes, especially in African American and postmenopausal women; it reports no new clinical findings.

This study suggests no significant association between vitamin D receptor gene polymorphisms and alopecia areata.

This review discusses inherited forms of vitamin D-dependent rickets and explains their genetic and metabolic causes but reports no new clinical findings.

In this study, researchers observed that the success of treating hereditary vitamin D–resistant rickets in children depends on the mutation location in the VDR gene, notably with favorable dental development outcomes for those with the p.R391S mutation, despite persistent alopecia.

This study found that the absence of vitamin D receptor-mediated suppression of PPARγ expression causes hair loss in VDR-null mice.

This study examines how the Severity of Alopecia Tool score was used to assess Alopecia Areata in patients while excluding systemic conditions that might affect vitamin D levels, but reports no new clinical results.

This study characterized two siblings with hereditary vitamin D resistant rickets and a mutation in the vitamin D receptor, finding no immune-related disorders despite a defective T cell response to vitamin D.

This review explores how vitamin D3 analogs could target various skin processes and diseases, potentially offering selective and effective treatments beyond psoriasis, but reports no new clinical findings.