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In this rodent study, researchers found that the drug finasteride may reduce anxiety and depression-like behaviors in a model of aging, despite inducing metabolic disturbances and depressive-like behaviors in young rats, suggesting potential considerations for its use in elderly populations.

In this study, subcutaneous injection of mesenchymal stem cell-conditioned medium promoted regeneration of mice skin aged by D-galactose, improving skin thickness, vascularization, and collagen density.

This study found that probiotics, specifically the L. plantarum MTCC 1325 strain, may have protective effects against Alzheimer's-like symptoms induced by D-Galactose in animal models, suggesting potential therapeutic use for neurodegenerative disorders.

In a study on mice, cow placenta extract showed strong antioxidant activities and reduced collagen damage, suggesting it could help delay skin aging caused by D-galactose.

This study found that topical mesenchymal stem cell conditioned medium improved skin structure by increasing collagen fiber density, hair follicles, and blood vessel number in a mouse model of skin aging.

This study explored the carbohydrate composition of plasma cell membranes in human embryonic epidermis over various gestational ages and found specific patterns that may inform future diagnostic and therapeutic approaches for dermatoses.

In this study, researchers found that long-term treatment with 5-alpha-reductase inhibitors improved depression-like symptoms more effectively than a short-term treatment followed by withdrawal in d-galactose-induced senescent male rats, by reducing brain inflammation and oxidative stress.

This study found that collagen and its compound may have antioxidant effects and reduce melanin in guinea pigs, while increasing skin moisture and hydroxyproline content in mice.

This study suggests that vitamin D-upregulated protein 1 (VDUP1) might play a unique role in regulating the differentiation of epidermal cells.

In this study, homozygous VDR null mutant mice exhibited nonfunctional vitamin D receptors, leading to growth abnormalities and revealing the limited physiological importance of vitamin D pathways outside the classical receptor.

This study found that the protein hairless acts as both a corepressor and coactivator of the vitamin D receptor, influencing gene transcription in a ligand-selective manner.

This study found that a novel missense mutation in the vitamin D receptor caused hereditary 1,25-dihydroxyvitamin D-resistant rickets with alopecia by disrupting protein function, highlighting the importance of DNA binding in hair development.

This study suggests that the vitamin D receptor and hairless gene may directly regulate each other via a transcriptional mechanism, potentially explaining phenotypic similarities between atrichia and VDRRIIa rickets.

This study created a humanized mouse model of hereditary vitamin D-resistant rickets that lacks alopecia, indicating the mutant receptor's potential to explore the syndrome's characteristics beyond vitamin D binding.

This narrative review examined skin-sparing techniques in gynecomastia surgery and found satisfactory thoracic remodeling with acceptable morbidity and reduced scarring, but acknowledged methodological differences that limit decisive conclusions.

In this study, iNKT10 cells were found to play a significant role in preventing and treating alopecia areata in a humanized mouse model, suggesting these cells could have potential in managing related autoimmune disorders.

In this study, a high-fat, high-cholesterol diet in atherosclerotic mice led to skin inflammation and hair problems, which could be reversed by inhibiting glycosphingolipid synthesis.

This study found that wet cupping blood differs significantly from venous blood in metabolite profiles, implying distinct biochemical pathways may be involved.

This study suggests that oxidative stress may contribute to androgenetic alopecia by inducing premature senescence and secretion of hair growth inhibitors in dermal papilla cells from balding scalp.

This study found that nonionic liposomes were the most effective vehicle for delivering reporter genes into the skin of rat pups, compared to other liposome and nonliposome formulations.

In this study, mouse amnion epithelium was successfully transformed into skin and hair follicles when associated with hair-forming dermis, revealing the necessity of specific influences for follicle formation.

This study found that the purified compound VB1 from Vitex negundo seeds may reduce UVA-induced skin aging by targeting MAPK1 and demonstrated its potential in mice.

This study found that while rat models treated with letrozole and dihydrotestosterone exhibit altered sterol, leukotriene, and steroid hormone profiles similar to human PCOS, significant differences remain.

This review highlights that Nyctanthes arbor-tristis contains numerous phytochemicals and has traditional uses for various conditions. It also reports pharmacological activities, suggesting potential benefits for diabetes, cancer, inflammation, and more.

This study found that astaxanthin effectively protected human dermal papillae cells from oxidative stress induced by hydrogen peroxide, reducing the percentage of cells expressing a stress marker significantly, suggesting potential benefits for hair loss treatment related to reactive oxygen species.

This study identified interactions between Vitamin D and Msx1 regulation pathways, noting that Msx1 overexpression decreases Vitamin D receptor expression in odontoblastic cells.

This study found that GALT5 and GALT2 are redundant enzymes essential for O-glycosylation of AGPs, with mutations leading to significant growth and development defects in plants.

This review reports that Fenugreek seeds contain compounds like Galactomannan and Trigonelline, which show anti-diabetic and anti-hyperlipidemic effects, while Fenugreek leaves have high saponin content, contributing to their anti-microbial activities.

This study found that the hairless gene product (Hr) suppresses VDR-mediated gene activation by directly interacting with the vitamin D receptor, potentially affecting hair follicle function.