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Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.

Alisertib was found to be an effective and tolerable treatment for children with recurrent brain tumors.

Researchers identified new compounds in Platycladi Cacumen and found variations in its flavonoid content, which could aid in its quality control.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.

New method uses hair follicle cells to estimate human body clock phase, potentially improving sleep disorder diagnosis.

Quickly get finasteride from tablets using easy methods.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

The new method is rapid, sensitive, and accurate for evaluating the quality of the medicinal herb Platycladi cacumen.

Combining mood stabilizers with antipsychotics is more effective for treating children with bipolar disorder than using mood stabilizers alone.

Male tissue has more cell death than female tissue after ischemia, and some neurosteroids only protect female cells.

Finasteride may increase suicide risk; more research needed.

Testosterone reduces heart damage and inflammation after injury.

Using 5-alpha reductase inhibitors may increase the risk of mild depression.

Caraway, Chinese chives, and cassia may improve health and prevent diseases due to their nutrients and medicinal properties.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Tretinoin gel is safe for sun exposure, but tacalcitol doesn't significantly improve non-segmental vitiligo.

Certain medications can reduce mortality risk in COPD patients, but others can increase risks of cardiovascular issues, postoperative delirium, and other adverse effects.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

The protein FLCN is involved in cellular cleanup and is regulated by ULK1.

Allopregnanolone changes gene expression in glioblastoma cells.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.

The document concluded that more research is needed to understand how estrogen affects the enzyme involved in hirsutism development.

Cirrhosis affects quality of life with various symptoms, requiring a holistic, multidisciplinary approach for management.

Tamsulosin increases the risk of floppy iris during eye surgery.