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Changes in genes FGA, VWF, and ACTG1 may contribute to pemphigus vulgaris.

This study investigated the effects of pathological α-synuclein on sebaceous gland cells in Parkinson's disease, finding that α-synuclein exposure altered cellular differentiation and lipid production, suggesting a potential link between α-synuclein and lipid dysregulation in the skin of PD patients.

This study found that in stretch-mediated tissue expansion, fibroblasts adopt an embryonic-like, low-collagen state that enhances epidermal stem cell renewal, supporting coordinated skin expansion crucial for reconstructive surgeries.

This study develops FR-1, a topical small molecule, which reduces scarring and avoids skin atrophy in a murine wound model, showing potential for treating fibrosis without the side effects of current therapies.

This study found that knocking down the gene SFRP1 in human hair follicles ex vivo prolonged the hair growth phase and increased keratinocyte proliferation, suggesting potential as a therapeutic target for maintaining hair growth in male pattern baldness, while DKK1 knockdown showed no effect.

This meta-analysis found that among topical OTC treatments for male androgenetic alopecia, minoxidil 5% applied twice daily was the most effective in increasing total hair density over 24 weeks.

This study used a novel extraction method to detect and measure mineralocorticoids and glucocorticoids in hair follicles, concluding these steroids may serve as effective biomarkers for diagnosing conditions related to steroid excess or deficiency, such as Cushing’s syndrome and congenital adrenal hyperplasia.

Regenerative medicine is effective and safe for treating vitiligo.

This study found that neurosteroids influence oxytocin secretion in sheep, particularly during stress and pregnancy, suggesting their role in protecting and maintaining pregnancy under harmful conditions.

This study demonstrated that a mechanical-chemical cascade involving dermal cell contraction and the activation of Piezo1 in epidermal cells is crucial for initiating interactions necessary for hair follicle regeneration in skin organoids.

In this study, researchers retrospectively analyzed five children with extensive and refractory alopecia areata treated with mesalazine, observing complete hair regrowth in all patients without side effects, suggesting potential benefits of this treatment combination, though controlled studies are needed for confirmation.

This study found that essential oils from Hedychium spicatum showed anti-inflammatory, antinociceptive, antipyretic, and antioxidant activities, with site-specific variations in their effectiveness.

This study observed that developing mammary organs in Monodelphis domestica show mammary hairs in 12-week-old females, which disappear by 18 weeks, with findings suggesting shared characteristics between their nipples and eutherian nipples, supporting the evolutionary link between mammary glands and hair organs.

In this animal study, applying a combination of inositol-stabilized arginine silicate complex and magnesium biotinate promoted hair growth but not nail growth.

In this study, a chronotherapeutic bilayer dressing system showed enhanced diabetic wound healing in a model by reducing inflammation through polyphenols and promoting repair with sustained PDGF-BB delivery, leading to faster re-epithelialization and hair follicle regeneration.

This study reviews the emerging role of protein S-palmitoylation in dermatology, highlighting its impact on skin functions like inflammation and barrier maintenance, and evaluating its potential as a therapeutic target for skin disorders such as alopecia and psoriasis.

In this study, a bidirectional Mendelian randomization analysis found a causal link between alopecia areata and hypothyroidism, indicating that each condition may influence the other, while no similar relationship was observed between androgenetic alopecia and hypothyroidism.

The researchers reported that an oral supplement containing hydrolysed fish-origin collagen, taurine, cysteine, methionine, iron, and selenium significantly improved the effectiveness of anti-hair loss treatments in people with androgenic alopecia or chronic telogen effluvium after 12 weeks, compared to drug treatments alone.

Scientists created human skin with hair from stem cells, which could help treat hair loss and skin conditions.

This study identified TGF-β2 as a crucial signal in hair follicle stem cell regeneration, highlighting its role in counteracting BMP signaling to promote tissue regeneration.

This study found that keratin and other hair proteins in humans are extensively modified posttranslationally, which helps explain the structural characteristics of mature hair.

This study found that methylprednisolone can block IgG-induced keratinocyte detachment in an animal model of pemphigus vulgaris, potentially by increasing the synthesis and modifying adhesion molecules.

In this study, manipulation of the enzyme 5α-reductase type 2 in human hepatocytes altered lipogenesis, suggesting clinical implications for patients using 5α-reductase inhibitors by affecting glucocorticoid action on hepatic lipid metabolism.

This study found that the antioxidant N-acetylcysteine attenuated ferroptosis in the uterus and placenta of a PCOS-like rat model, indicating its potential as a therapeutic strategy for PCOS-related complications.

This review discusses the potential of Lansium domesticum as a herbal medicine, summarizing its traditional uses, nutritional value, bioactivities, and related nanoparticles and pharmaceutical formulations, but reports no new experimental results.

This study found that chronic low-grade inflammation exists independently of excess weight or obesity in women with PCOS, with notable increases in specific cytokines such as IL-9, MCP-3, and MIP-1α.

This study found that the acyl-CoA binding protein is essential for the production of very long chain free fatty acids in the stratum corneum and maintaining normal epidermal barrier function in mice.

This study suggests that the period from birth to 6 months is optimal for regulating secondary hair follicle development in cashmere goats, with specific growth factors potentially playing a regulatory role.

This study found that melanin granules in black human hair are key dyeing regions for oxidative hair coloring, as confirmed by nanoscale mass spectrometry analysis detecting deuterium ions.

This study found that hair shaft miniaturization in aging and genetic hypotrichosis leads to hair follicle stem cell loss through mechanical compression and apoptosis mediated by the Piezo1 channel.