20 citations
,
June 2014 in “BMC genomics” This study identified the placenta at the base of the ovary as the origin of poplar seed hair development and detailed transcriptome dynamics during the growth process.
11 citations
,
September 2023 in “Nature Communications” In this study, researchers found that the cell surface protein Lrig1 plays a crucial role in regulating the suppressive function of regulatory T cells, suggesting it as a potential target for treating autoimmune diseases, as evidenced by experiments in mouse models.
3 citations
,
August 2020 in “Nutrition Journal” This study found that spinach-derived thylakoid supplementation, combined with a calorie-restricted diet, led to more significant improvements in weight loss and insulin sensitivity in obese women with PCOS than calorie restriction alone.
1 citations
,
February 2025 in “International Journal of Molecular Sciences” This study found that supplementing Liaoning cashmere goats with HMBi increased cashmere length while decreasing its diameter, attributed to changes in Met-related metabolites and elevated expression of genes related to the Met cycle and cell differentiation pathways such as Wnt and MAPK.
August 2024 in “Dermatology and Therapy” This report describes a case where a 44-year-old male treated with vorasidenib for diffuse low-grade gliomas developed unexpected hair growth, including in areas of severe hair loss, after one month, highlighting a previously undocumented side effect.
December 2022 in “Scientia Pharmaceutica” This study found that platelet-rich plasma (PRP) was more effective than minoxidil 5% topical treatment in increasing hair density for androgenic alopecia patients and had an additional benefit when combined with minoxidil.
January 2022 in “Stem cell biology and regenerative medicine” This review explores the complex interactions between hair follicle stem cells and surrounding structures that are essential for understanding hair regeneration, reporting no new experimental results.
November 2024 in “PubMed” This study found that carboxytherapy significantly improved skin wrinkles, laxity, and pigmentation among 28 patients with skin aging on the abdomen, accompanied by increased epidermis and dermis thickness and no significant side effects.
67 citations
,
May 2014 in “International Journal of Molecular Sciences” This review outlines the role of dermal fibroblasts in wound healing and highlights their potential in developing new cellular therapies, but reports no new clinical results.
24 citations
,
April 2014 in “Oncotarget” This study found that minoxidil suppressed androgen receptor functions and stability, suggesting its potential use in treating diseases related to the androgen-AR pathway.
22 citations
,
January 2014 in “Journal of Interferon & Cytokine Research” In this study, researchers found that specific IL18 genetic variants may be linked to increased susceptibility to alopecia areata in a Korean population.
4 citations
,
July 2025 in “Molecular Diversity” This review outlines drug repurposing as an efficient, low-cost strategy to identify new uses for existing drugs, highlighting various computational and experimental approaches as well as publicly available databases to aid in personalized pharmacotherapy.
1 citations
,
April 2025 in “Scientific Reports” This study developed a culture method to expand and differentiate primary mammary basal cells, identifying key transcription factors like EGR1 and ELF3 that influence Claudin expression and actin organization, offering insights into epithelial cell biology and potential applications in related research fields.
September 2025 in “Dermatology and Therapy” This systematic review and meta-analysis found that platelet-rich plasma (PRP) therapy is effective in increasing hair density and reducing hair loss for alopecia, with variations in response based on activation status.
July 2025 in “Scientific Reports” In this study, researchers identified six novel prognostic biomarkers for bladder cancer and developed a predictive model that effectively stratifies patients into high-risk and low-risk groups based on immune cell infiltration differences and gene expression.
May 2025 in “Animal Bioscience” This study found that inhibiting prolactin secretion during the telogen phase can reduce the number of activated secondary hair follicles and the width of hair bulbs.
June 2025 in “Clinical Cosmetic and Investigational Dermatology” This report presents a case where a 17-year-old male developed severe unilateral alopecia following radiotherapy for pediatric glioblastoma multiforme, which did not respond to minoxidil or platelet-rich plasma treatments.
1 citations
,
June 2025 in “Journal of Materials Science Materials in Medicine” This study reports that multifunctional electrospun scaffolds containing silver vanadate, hydroxyapatite, and graphene oxide significantly improved wound healing in a rat model, promoting rapid re-epithelialization, enhanced mechanical properties, and strong antibacterial activity, making them promising candidates for advanced wound care applications.
August 2025 in “Animal Bioscience” In this study, researchers examined the methylation patterns in the skin tissues of Alpine Merino sheep with varying wool fiber diameters, finding that specific methylated RNAs linked to the Wnt, Notch, and TGF-ẞ signaling pathways may influence fiber diameter and potentially improve wool quality.
August 2025 in “Dermatology and Therapy” This study conducted a meta-analysis of gene expression data from alopecia areata patients, identifying 5109 differentially expressed genes and highlighting enriched pathways like JAK-STAT signaling, providing insights into the disease's pathogenesis and potential treatment targets.
4 citations
,
December 2021 in “Archivio italiano di urologia andrologia” This review found that patients taking antiandrogens, 5 alpha-reductase inhibitors, and spironolactone have an increased risk of developing gynecomastia, potentially due to hormonal changes.
3 citations
,
August 2025 in “Cell” Fibroblast bioelectric signaling can promote hair growth and may help treat hair loss.
1 citations
,
February 2025 in “Journal of the Neurological Sciences” This study suggests that BTP levels in cerebrospinal fluid might help diagnose CIDP and predict therapy response but require validation in larger cohorts.
July 2025 in “Journal of Dermatological Treatment” This study found that platelet-rich plasma significantly improved hair growth parameters in androgenic alopecia patients and was even more effective when combined with minoxidil, particularly in reducing vellus hair.
4 citations
,
May 2025 in “Stem Cell Research & Therapy” This review explores the potential of extracellular vesicle therapy as a novel strategy to delay intervertebral disc degeneration and enhance tissue repair, by modulating key pathogenic mechanisms, with a focus on the molecular components and bioengineering modifications of extracellular vesicles.
4 citations
,
May 2025 in “Cells” This study found that miR-370-3p targets SMAD4 to inhibit cell proliferation, promote apoptosis, and affect the cell cycle in follicular papilla cells, demonstrating differences in their expression in sheep tissues, which may impact hair follicle development.
1 citations
,
April 2025 in “Journal of Cosmetic Dermatology” This study found that using Alastin Restorative Skin Complex Serum 2.0 with TriHex Technology for 12 weeks significantly improved facial skin hydration, elasticity, and overall quality in individuals with moderate to severe skin aging, with histological evidence showing new collagen and elastin fibers.
1 citations
,
January 2025 in “Veterinary Medicine International” This review found promising benefits of platelet-rich plasma for treating ocular surface diseases in animals, but methodological flaws currently preclude recommending it as standard care.
1 citations
,
August 2025 in “Frontiers in Bioengineering and Biotechnology” This study found that a 3D wound model, the 3DWoundSE, showed improved responsiveness to injury and cytotoxic stimuli compared to an intact 3D skin equivalent, offering a reproducible and ethical alternative to animal models for early wound response assessment in dermatological research and drug development.
August 2025 in “The Journal of Sexual Medicine” This retrospective pharmacovigilance study identified 34 drugs, including finasteride and dutasteride, that may be associated with sexual dysfunction, with a higher risk observed in males aged 31-45.