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Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.

PGD2 stops hair growth and is higher in bald men with AGA.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Remove inflamed cysts surgically, avoid topical antibiotics on wounds, treat skin and mouth conditions with specific medications, and address underlying causes of hair loss.

Some alternative treatments for hair loss might work, but more research is needed.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

15-lipoxygenase helps keep skin healthy by reducing inflammation.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

Spinach-derived thylakoid supplements plus a low-calorie diet helped obese women with polycystic ovary syndrome lose weight and improve their metabolism.

Using cetirizine on the skin and taking vitamin D can help increase hair growth in children with hair loss from ectodermal dysplasia.

Miliacin with polar lipids helps hair growth and improves hair loss in women.

Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.

Some treatments can help hair regrowth in alopecia areata, but none offer a cure, and effectiveness varies.

Targeting the PGD2-DP2 pathway may help treat hair loss.

Adults should not consume more than 255 micrograms of selenium per day to avoid risk of hair loss and other side effects.

People with Alopecia areata often have lower Vitamin D levels, which might affect the severity of their condition.

Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.

People with androgenetic alopecia have different lipid levels in their blood, which vary between men and women, and may be linked to a higher risk of metabolic syndrome.

Targeting CXXC5 and GSK-3β may help treat male pattern baldness.

Vitamin B6 helps increase hair growth and density in rabbits by affecting certain cell signaling pathways.

High DHA levels delay wound healing and worsen skin repair quality.

The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.

CEC levels may be a useful marker for predicting prostate cancer progression.

Blood tests for tumor cells could improve prostate cancer diagnosis and treatment; hair loss severity linked to a gene affecting prostate conditions.

The document concludes that a new biosensor can efficiently detect prostate cancer cells and that standardized referrals help find significant cancers effectively.

Gene variation affects prostate issues and hair loss.

The document concludes that more research is needed to understand how to treat muscle pain with drugs.