research From Genotoxic Stresses to Skin Damage: Distinct, Novel Mechanisms of Skin and Hair Damage in Chemo/Radiation Therapy
Chemotherapy and radiation therapy cause skin and hair damage by altering gene expression and signaling pathways.
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390-420 / 990 results research Pili Trianguli Et Canaliculi Is a Defect of Inner Root Sheath Keratinization
The hair defect is due to abnormal inner root sheath keratinization.
research α3β1-Integrin Regulates Hair Follicle But Not Interfollicular Morphogenesis in Adult Epidermis
α3β1-integrin is crucial for maintaining normal hair follicle shape and function but not needed for the development of the surrounding skin.
research Hair: The Most Sophisticated Biological Composite Material
Hair is a complex protein fiber with unique properties useful for developing hair products.
research Differential Gene Expression Analysis Between Anagen and Telogen of Capra Hircus Skin Based on the De Novo Assembled Transcriptome Sequence
Signaling pathways are crucial for hair growth in goats.
research Comparative Proteomic Analysis of Male and Female Androgenetic Alopecia: Elucidating Gender-Specific Molecular Patterns
Male and female pattern hair loss have different molecular pathways, suggesting unique treatment targets for each sex.
research A 3D Microtumour System That Faithfully Represents Ovarian Cancer Minimal Residual Disease
The study developed a 3D model that closely imitates remaining ovarian cancer after treatment and identified a potential drug targeting resistant cancer cells.
research Keratin Function and Regulation in Tissue Homeostasis and Pathogenesis
Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.
research Bone-Forming Cells with Pronounced Spread into the Third Dimension in Polymer Scaffolds Fabricated by Two-Photon Polymerization
Bone-forming cells grow well in 3D polymer scaffolds with 35 µm pores.
research Alpha-Parvin Is Required for Epidermal Morphogenesis, Hair Follicle Development, and Basal Keratinocyte Polarity
α-parvin is necessary for skin and hair growth and for the correct orientation of skin cells.
research Hypaphorine, an Indole-3-Acetic Acid Antagonist Delivered by the Ectomycorrhizal Fungus Pisolithus Tinctorius, Induces Reorganization of Actin and the Microtubule Cytoskeleton in Eucalyptus Globulus ssp. Bicostata Root Hairs
Hypaphorine from a fungus changes the internal structure of Eucalyptus root hairs, stopping their growth.
research A Novel Mutation in the FERMT1 Gene in a Spanish Family with Kindler’s Syndrome
Researchers found a new mutation in the FERMT1 gene in a Spanish family with Kindler syndrome.
research Keratin 75 Is a Component of the LINC Complex and Has an Essential Role in Mediating the SOX2 Rapid Healing Response During Wound Repair
Keratin 75 is important for fast wound healing and works with SOX2 and the LINC complex to help skin cells move and repair damage.
research Molecular Genetics of Inherited Disorders of Epidermal Keratins
Mutations in keratin genes cause skin disorders, but new treatments show promise.
research Characteristics of KRT80 and Its Roles in Neoplastic Diseases
KRT80 may worsen cancer by increasing growth and spread, but its full effects on treatment and outcomes need more research.
research Erythrocyte Deformability and Hereditary Elliptocytosis
Hereditary elliptocytosis causes elongated red blood cells and can lead to mild or no symptoms.
research Expression of Plectin-1 and Trichohyalin in Human Tongue Cancer Cells
Tongue cancer cells show more plectin-1 than non-cancer cells, but both have similar levels of trichohyalin.
research Epidermolysis Bullosa Simplex Keratinocytes Show Disturbed Mitochondrial Positioning and Activity
Skin cells from people with Epidermolysis Bullosa Simplex have abnormally placed and less active mitochondria.
research Deciphering the Role of the Hexosamine Pathway in Skin Homeostasis
The hexosamine pathway helps protect skin cells from stress and may improve skin and hair health.
research The Use of Ultrasound-Targeted Microbubble Destruction Technology for Drug Delivery and Gene Transfection in the Treatment of Atherosclerosis
GSK-36 downregulation with UTMD improves plaque stability in atherosclerosis treatment.
research Hydrogen Sulfide Disturbs Actin Polymerization via S-Sulfhydration Resulting in Stunted Root Hair Growth
Hydrogen sulfide disrupts protein function and root hair growth in plants by modifying proteins.
research Desmoglein 4 Is Regulated by Transcription Factors Implicated in Hair Shaft Differentiation
Desmoglein 4 is controlled by specific proteins that affect hair growth.
research Allopregnanolone Alters the Gene Expression Profile of Human Glioblastoma Cells
Allopregnanolone changes gene expression in glioblastoma cells.
research Loss of Keratin 10 Is Accompanied by Increased Sebocyte Proliferation and Differentiation
Without keratin 10, there's more growth and development of oil-producing skin cells.
research Evolution of Trichocyte Keratins
Hair keratins evolved from ancient proteins, diversifying through gene changes, crucial for forming claws and later hair in mammals.
research Biology of the Skin and Dermatological Disease
Knowing how skin works and its diseases helps doctors diagnose and treat skin conditions better.
research Interleukin-1 Induces Transcription of Keratin K6 in Human Epidermal Keratinocytes
Interleukin-1 increases keratin K6 production in skin cells.
research Spatiotemporal Antagonism in Mesenchymal-Epithelial Signaling in Sweat Versus Hair Fate Decision
Sweat glands and hair follicles are determined by opposing signals, with BMPs promoting sweat glands and blocking BMPs leading to hair follicles.
research Exploring the Thyroid-Skin Connection: Concepts, Questions, and Clinical Relevance
Thyroid function affects skin health, with a complex interaction between the two.
research Increased Expression of Zyxin and Its Potential Function in Androgenetic Alopecia
Inhibiting Zyxin may help treat androgenetic alopecia by promoting hair growth.