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Hair and nail cells share similar proteins, indicating a common differentiation pathway.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Fat cells help recruit healing cells and build skin structure during wound healing.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Calcium affects where root hairs grow, but other unknown factors determine their growth direction.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Stem cell self-renewal is complex and needs more research for full understanding.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.

K6hf is a unique protein found only in a specific layer of hair follicles.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

One minoxidil-sensitive potassium channel exists in human hair follicles.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.