7 citations,
June 2022 in “Frontiers in Medicine” ADSC-derived extracellular vesicles show promise for skin and hair regeneration and wound healing.
5 citations,
December 2022 in “Toxins” Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.
3 citations,
March 2023 in “International journal of molecular sciences” Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.
2 citations,
November 2023 in “Biomolecules” WNT signaling is crucial for skin development and healing.
1 citations,
July 2021 in “IntechOpen eBooks” Environmental factors can cause mutations in skin proteins, leading to skin disorders.
June 2024 in “International journal of molecular sciences” Adenosine complex helps increase hair thickness and density in hair loss.
April 2024 in “International journal of molecular sciences” Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.
February 2024 in “Medicina” AFM can diagnose hair disorders by revealing detailed hair surface changes.
August 2023 in “International Journal of Nanomedicine” A new wound healing treatment using a graphene-based material with white light speeds up healing and reduces infection and scarring.
January 2022 in “Archiv für Tierzucht” EPHA4 and Ephrin A3 are found in the skin of Aohan fine-wool sheep.
467 citations,
May 1999 in “Molecular Cell” The study explored the effects of activating the protooncogene c-Myc in the skin of transgenic mice, revealing that c-Myc activation led to rapid proliferation and disrupted differentiation of keratinocytes, resulting in conditions resembling precancerous lesions such as hyperplastic actinic keratosis. These changes were accompanied by angiogenesis and were reversible upon deactivation of c-Myc. Despite the potential for c-Myc to induce apoptosis, survival signals in the skin suppressed this effect, allowing for the development of benign, hyperproliferative lesions without progressing to malignancy. The study highlighted the role of c-Myc in skin homeostasis and its implications in skin carcinogenesis, suggesting that additional mutations would be necessary for malignant transformation.
154 citations,
November 2017 in “Development” Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.
136 citations,
September 2019 in “Journal of Clinical Investigation” Dermal adipose tissue in mice can change and revert to help with skin health.
133 citations,
July 2020 in “Cells” Creating fully functional artificial skin for chronic wounds is still very challenging.
119 citations,
June 2021 in “Heliyon” The review on Glycyrrhiza glabra, or licorice, highlighted its diverse phytochemical constituents and pharmacological activities, noting compounds like glycyrrhizin for their anti-cancer, anti-inflammatory, and antimicrobial effects. Licorice was recognized for stimulating hair growth, showing better results than 2% minoxidil in treating alopecia. It also provided benefits such as controlling obesity, hepatoprotection, and memory enhancement. The review compiled data from 144 articles, emphasizing traditional uses and potential side effects. Licorice exhibited anticoagulant, antimalarial, and antispasmodic activities, and showed promise in managing diabetes, dyslipidemia, and various cancers. Despite its therapeutic potential, the review cautioned about possible toxicological effects and the need for controlled use and further research.
114 citations,
January 2016 in “Current topics in developmental biology/Current Topics in Developmental Biology” Frizzled receptors are essential for various body development processes and maintaining certain body functions.
81 citations,
February 2016 in “Veterinary pathology” Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.
47 citations,
August 2016 in “American Journal Of Pathology” Fibroblast changes in systemic sclerosis may help understand disease severity and treatment.
31 citations,
April 2015 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Androgens cause oil-producing skin cells with androgen receptors to mature and produce more oil.
30 citations,
August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” TGase 3 helps build hair structure by forming strong bonds between proteins.
22 citations,
July 2020 in “iScience” Sox21 is crucial for tooth development and enamel formation by preventing cells from changing into a different type.
21 citations,
July 2022 in “Orphanet journal of rare diseases” New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.
14 citations,
June 2022 in “BMC genomics” Key genes crucial for sheep hair follicle development were identified, aiding fine wool breeding and human hair loss research.
12 citations,
April 2015 in “BMC research notes” Root hairs in cereal crops can grow beyond the usual zone, and using Turface® clay helps study this.
9 citations,
April 2019 in “Bioscience, biotechnology, and biochemistry” Ten miRNAs may play key roles in starting secondary hair follicle development in sheep foetuses.
8 citations,
March 2022 in “Journal of The Taiwan Institute of Chemical Engineers” Extracts from a type of brown seaweed can help promote hair growth.
7 citations,
August 2022 in “Journal of Nanobiotechnology” Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.
7 citations,
March 2022 in “Frontiers in Genetics” The research found specific genes that may cause longer hair in Tianzhu White Yak.
7 citations,
February 2022 in “Stem cell reviews and reports” Skin cells show flexibility in healing wounds and forming tumors, with potential for treating hair disorders and chronic ulcers.
6 citations,
August 2023 in “BMC genomics” The study found that genetic differences related to hair growth and other traits help cashmere goats adapt to high-altitude environments.