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Blocking IL-1 could help treat some hair loss conditions; alopecia affects liver detox systems; spironolactone is better than finasteride for female hair growth; focusing on the catagen hair phase could lead to new alopecia treatments.

Blocking a specific immune cell signal can trigger hair growth.

Prolactin may be important for skin growth and immune function.

IL-15 helps maintain hair growth and protects the immune status of hair follicles.

Thymic stromal lymphopoietin (TSLP) promotes hair growth by stimulating specific skin cells.

Immune changes and specific genes contribute to male hair loss.

Blocking EGFR in skin cells doesn't majorly increase inflammation markers.

Blocking certain pathways with kinase inhibitors may help treat cutaneous lupus erythematosus.

Activins and follistatins, part of the TGFβ family, are crucial for hair follicle development and skin health, affecting growth, repair, and the hair cycle.

Oestrogen and thyrotropin-releasing hormone affect prolactin and its receptor in human skin and hair, suggesting new treatment options for related conditions.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.

Skin has specialized touch receptors that can tell different sensations apart.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.

The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.

Alopecia areata involves specific T-cells, unlike androgenetic alopecia.

Chemotherapy and cytokine therapy can cause various skin reactions, including hair loss and hypersensitivity.

Clascoterone is a new, effective, and safe acne treatment without systemic side effects.

The study concluded that both estrogen and androgen receptors, which decrease with age, are linked to skin aging and may be hormonally regulated.

Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.

Removing the ROBO4 gene in mice reduces skin inflammation and hair loss by affecting certain inflammation pathways and gene expression.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

VEGF and its receptor might cause hair loss.

New cytokine-targeted therapies show promise for treating alopecia areata.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.