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Human skin can make serotonin and melatonin.

Estrogen therapy can reduce skin aging but has cancer risks.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.

Antioxidants can benefit skin health but should be used carefully to avoid negative effects.

Animal models have helped understand hair loss from alopecia areata and find new treatments.

The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.

New treatments for Alopecia Areata, like JAK inhibitors, show promise for hair regrowth and are likely to change future treatment approaches.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

Human hair follicles produce and respond to erythropoietin, helping protect against stress.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Both ruxolitinib and tofacitinib are effective and safe for treating severe alopecia areata, but relapses are common.

Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.

Hydrogels could lead to better treatments for wound healing without scars.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

Premature graying of hair may suggest health issues and currently lacks effective treatments.

Disrupting Acvr1b in mice causes severe hair loss and thicker skin.