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Aging causes skin stem cells to work less effectively.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.

Skin problems in COVID-19 patients are rare and may be due to the body's complex immune response or blood clotting issues.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.

Corticosteroid treatment reduces inflammation and alters hair keratins in alopecia areata.

Children with atopic dermatitis often have sleep problems due to itching and may benefit from melatonin, which helps with sleep and skin symptoms.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

Stem Cell Educator therapy helps regrow hair and improve life quality in alopecia areata patients.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

DPCP helps treat severe hair loss, but 5% minoxidil doesn't add benefits.

Prolactin may be important for skin growth and immune function.

Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.

Severe COVID-19 may cause hair loss, and doctors recommend supplements and topical treatments to manage it.

COVID-19 infection may trigger alopecia areata in some patients.

SACUMAN, a rare condition causing hair loss without clear signs, is often misdiagnosed and needs scalp biopsies for accurate detection.

The document concludes that treating tough skin disease in lupus involves sun protection, steroids, antimalarials, and various other therapies chosen based on individual risks and benefits.

AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

COVID-19 infection can significantly cause temporary hair loss.

An 81-year-old man's white hair began to regain its original color while he was treated with lenalidomide, suggesting that graying hair might be reversible.

Nonantibiotic macrolides show promise for treating various inflammatory skin conditions.

Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.

COVID-19 may cause hair loss and scalp pain due to inflammation and changes in hair follicle receptors, but these symptoms typically resolve in 2 to 4 months.

Psoriasis or contact dermatitis can override alopecia areata, allowing hair growth.

Old treatments for other skin conditions showed promise for hair regrowth in mice with a hair loss condition.