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Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

Polymeric nanoparticles show promise for treating skin diseases.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

PGD2 stops hair growth and is higher in bald men with AGA.

Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Wnt ligands are crucial for hair growth and repair.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

CDP is crucial for lung and hair follicle cell development.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.