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Spironolactone is a safe and effective treatment for reducing excessive hair growth in women.

Spironolactone helps regrow hair in women with hair loss.

Ketoconazole cream is effective for skin conditions like seborrheic dermatitis and may help with hair loss and other skin issues, with generally mild side effects.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.

Genetic mutations can affect female sexual development, requiring personalized medical care.

The Rotterdam Study investigates diseases in older adults and has produced many research findings.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

The Rotterdam Study aims to understand various diseases in older adults.