Search

everythinglearnresearchcommunity

for

Search:↓

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Selenium might help with insulin resistance and cholesterol in PCOS, but more research is needed to confirm its benefits.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

DHT affects testicular development and regulates spermatogenesis in some fish.

Polycystic ovary syndrome causes high male hormone levels, leading to symptoms like excess hair, acne, and fertility problems.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Statins may help treat PCOS by lowering androgen levels and improving cholesterol.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Oxidative stress worsens PCOS by damaging cells and disrupting metabolism, suggesting antioxidant treatments might help.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

Researchers found two enzymes in Avicennia marina that help produce maslinic acid and corosolic acid, which have medicinal benefits.

Eicosanoids are crucial for skin health, and targeting their pathways may help treat skin conditions.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.

Nonclassic congenital adrenal hyperplasia is a genetic disorder causing hormone imbalances, affecting fertility and requiring personalized treatment.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

Adding a specific gene to skin cells can help treat skin disorders like psoriasis.

The vitamin D receptor can work without its usual activating molecule.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

FA2H is essential for normal fur and sebum production in mice.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Genetics play a role in acne, but how exactly they contribute is not fully understood.