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Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

New ABCA12 gene mutations were linked to a skin condition with scaling and hair loss, and a treatment helped with hair loss in a related case.

The method reliably profiles eicosanoids and shows epitestosterone reduces their levels, similar to common anti-inflammatory drugs.

The document concludes that there are various causes and treatments for hair loss, with hair transplantation being a notable option.

Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.

The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.

The document concludes that effective acne treatment requires a personalized combination of therapies and long-term commitment, with retinoids being important for maintenance.

Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.

Improved Finasteride delivery for hair loss treatment.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.

New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.

Certain drugs that block specific enzymes can help treat prostate diseases.

Cyclophosphamide often causes gastrointestinal issues, hair loss, and low blood cell counts in Chinese patients with autoimmune diseases.

Indigenous herbal medicines in the Indian subcontinent have potential for drug development but need more research and standardization.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

Statins may help treat PCOS by lowering androgen levels and improving cholesterol.

To treat tinea capitis in children, oral antifungal medication is necessary, with newer drugs offering shorter treatment times than the traditional griseofulvin.

Higher BPA levels may be linked to idiopathic hyperandrogenemia in women.

Acne can be managed with various treatments and requires psychological support due to its emotional impact.

The document concludes that various drugs for men's health issues are in development, with treatments for sexual dysfunction and prostate conditions being the most advanced.

Centratherum anthelminticum seed extract effectively treats Polycystic Ovary Syndrome in rats.

Finasteride effectively treats baldness but may cause sexual side effects.

Shell ginger contains kavalactones that promote hair growth and have anti-cancer, anti-inflammatory, and anti-obesity effects.

Compound 7b is a promising candidate for treating benign prostatic hyperplasia and prostate cancer.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Certain drugs, especially antiandrogens and spironolactone, significantly increase the risk of gynecomastia.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Long-term use of finasteride in women can cause hormonal changes, DNA damage, and menstrual issues.