research Self-Assembled Complete Hair Follicle Organoids by Coculture of Neonatal Mouse Epidermal Cells and Dermal Cells in Matrigel
Scientists created complete hair-like structures by growing mouse skin cells together in a special gel.
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research The Biology of Hair Follicles
Hair follicle biology advancements may lead to better hair growth disorder treatments.
research Nerve-Derived Sonic Hedgehog Defines a Niche for Hair Follicle Stem Cells Capable of Becoming Epidermal Stem Cells
Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.
research Primary Scarring Alopecias: Review of Histopathological Findings of 37 Patients from the Department of Dermatology at the Hospital das Clínicas, Faculty of Medicine, University of São Paulo from 2000 to 2005
Accurate diagnosis of cicatricial alopecias requires thorough scalp examination and multiple biopsy techniques.
research Finasteride Blocks the Reduction in Ictal Activity Produced by Exogenous Estrous Cyclicity
research Self-Organizing Hair Peg-Like Structures From Dissociated Skin Progenitor Cells: New Insights for Human Hair Follicle Organoid Engineering and Turing Patterning in an Asymmetric Morphogenetic Field
Researchers created early-stage hair-like structures from skin cells, showing how these cells can self-organize, but more is needed for complete hair growth.
research Epidermal Abnormalities and Increased Malignancy of Skin Tumors in Human Epidermal Keratin 8-Expressing Transgenic Mice
Mice with human skin protein K8 had more skin problems and cancer.
research Hairless: A Nuclear Receptor Corepressor Essential for Skin Function
The Hairless gene is crucial for healthy skin and hair growth.
research Modulation of Hair Growth with Small Molecule Agonists of the Hedgehog Signaling Pathway
Applying a special compound can promote hair growth without harmful side effects.
research Biomedical Applications of Organoids in Genetic Diseases
Organoids help study and treat genetic diseases, offering personalized medicine and therapy testing.
research Finasteride Induces Cytoarchitectural Alterations in Hippocampus of Adult Male Wistar Rat: A Contributor to Neuropsychiatric Effects of Post-Finasteride Syndrome
Finasteride may cause memory problems by damaging the hippocampus.
research Molecular Histology in Skin Appendage Morphogenesis
New molecules involved in skin and hair growth were identified, improving understanding and future treatments.
research Translational Frontiers: Insight From Lymphatics in Skin Regeneration
Lymphatic vessels are important for skin repair and could affect skin disease treatments.
research Biology of Hair Growth
Testosterone and dihydrotestosterone affect hair growth, and new techniques like the folliculogram help study it, but fully understanding hair growth is still complex.
research Dynamics and Epigenetics of the Epidermal Differentiation Complex
Epigenetic mechanisms control skin development by regulating gene expression.
research Laminin 332 Is Indispensable for Homeostatic Epidermal Differentiation Programs
Laminin 332 is essential for normal skin cell behavior and structure.
research Emerging Role of ILK and ELMO2 in the Integration of Adhesion and Migration Pathways
ILK and ELMO2 help cells move and stick together, important for wound healing and hair growth.
research Keratin K15 as a Biomarker of Epidermal Stem Cells
Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.
research Epidermolysis Bullosa Simplex: A Paradigm for Disorders of Tissue Fragility
Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.
research Cell Death by Cornification
Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.
research Advanced Nanocarrier- and Microneedle-Based Transdermal Drug Delivery Strategies for Skin Diseases Treatment
Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
research The Anxiolytic-Like Effects of Estazolam on a PTSD Animal Model
Estazolam reduces anxiety-like behavior in PTSD by increasing allopregnanolone levels.
research Cornification
Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.
research The Dark Side of 5α-Reductase Inhibitors' Therapy: Sexual Dysfunction, High Gleason Grade Prostate Cancer, and Depression
5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.
research Shedding Light on the Effects of Calorie Restriction and Its Mimetics on Skin Biology
Eating fewer calories may slow skin aging and improve skin health through various biological changes.
research Orchestration of Tissue-Scale Mechanics and Fate Decisions by Polarity Signaling
Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.
research Dermal Niche Signaling and Epidermal Stem Cells
Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
research Post-Finasteride Syndrome: When Will We Get the Courage to Fight the Dictating Pharma Industry Despite Awareness of Sexual, Neurological, and Metabolic Side Effects in Young Men for Over a Decade
Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.
research Integration of Biochemical and Mechanical Signals at the Nuclear Periphery: Impacts on Skin Development and Disease
The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.
research All Roads Lead to the Nucleus: Integration of Signaling, Transcription Factor-Mediated, and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration
The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.