January 1974 in “Nippon Nōgei Kagakukaishi/Nihon Nougei Kagakkaishi” Applying L-methionine and L-serine to the skin promotes the most hair growth.
215 citations,
March 2018 in “Archives of Toxicology” Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.
68 citations,
January 2022 in “International Journal of Molecular Sciences” PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.
56 citations,
September 2013 in “Journal of Biochemistry and Molecular Biology” Androgens increase a growth factor in hair cells by creating reactive oxygen species, and antioxidants might help treat hair loss.
34 citations,
January 2011 in “Fundamental & Clinical Pharmacology” New treatments for PCOS show promise, but no current medication treats all aspects of the condition.
24 citations,
May 2006 in “Proceedings of the National Academy of Sciences of the United States of America” Budesonide and N-acetylcysteine reduced tumors and alopecia in mice, regardless of FHIT gene status.
9 citations,
September 2017 in “Journal of Investigative Dermatology Symposium Proceedings” Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, and antioxidants may help treat hair loss.
4 citations,
May 2023 in “Pigment Cell & Melanoma Research” BMI1 is essential for preventing hair greying and maintaining hair color.
4 citations,
January 2014 in “Indian dermatology online journal” Monilethrix is a genetic hair disorder causing fragile, beaded hair with no effective treatment.
2 citations,
January 2012 in “Journal of metabolic syndrome” The document concludes that hirsutism can be managed with various treatments tailored to the individual, potentially improving quality of life.
August 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Particulate matter causes inflammation in hair cells, potentially harming hair growth.
January 2020 in “Korean journal of ophthalmology/Korean Journal of Ophthalmology” Minoxidil increases cell layer permeability by reducing tight junction proteins and raising ROS levels.
May 2017 in “InTech eBooks” Hair pulling disorder is treated with therapy and medication; hair loss from tension can be reversed if caught early.
January 2009 in “Elsevier eBooks” Some plant-based treatments may help with ovary function, insulin resistance, and excess male hormones in PCOS, but more research is needed to confirm their safety and effectiveness.
June 2002 in “Science of aging knowledge environment” The cancer gene c-Myc increases harmful chemicals that damage DNA and can lead to cancer, but antioxidants can reduce this damage.
Penicillamine can cause taste problems due to copper loss, which can be fixed with copper or zinc supplements.
87 citations,
January 1996 in “Journal of cellular biochemistry” Over 30 potential cancer prevention treatments are being tested, with some showing promise in early research.
83 citations,
July 2008 in “Current Opinion in Chemical Biology” The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.
25 citations,
September 2014 in “SpringerPlus” The study identified a new keratin-associated protein gene, KAP8-2, in sheep, which was absent in humans. This gene, located on sheep chromosome 1, exhibited two sequence variants and was rich in glycine and tyrosine but low in cysteine, with a unique high content of acidic amino acids. The research, involving 208 New Zealand Romney-cross sheep, suggested that KAP8-2 might play a role in the unique properties of sheep wool compared to human hair. The findings provided insights into genetic differences between species and contributed to the understanding of hair and wool fiber formation.
11 citations,
July 2014 in “Gene” The S250C variant in a gene may cause autoimmunity and immunodeficiency by impairing protein function.
11 citations,
October 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” A mutation in the KRT71 gene causes a hair disorder by disrupting hair follicle structure and texture.
2 citations,
February 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” The Asiatic lion has very low genetic diversity and unique genetic traits, highlighting the need for its conservation.
2 citations,
July 2013 in “Journal of Animal Physiology and Animal Nutrition” The study aimed to determine differences in felinine excretion among domesticated cat breeds by analyzing urine samples from 83 entire male cats across eight breeds in the Netherlands. The felinine:creatinine (Fel:Cr) ratio was used to account for variations in renal output. The Abyssinian and Sphynx breeds had the highest Fel:Cr ratios (0.878), significantly differing from British Shorthairs, Birmans, Norwegian Forest cats, and Siberian cats. Persians and Ragdolls showed no significant difference from other breeds. The variation in Fel:Cr ratios was partly explained by hair growth, as felinine production and hair growth compete for cysteine. Shorthaired and hairless breeds generally had higher Fel:Cr ratios than longhaired breeds, except for Persians. Further research was suggested to explore the impact of hair growth on felinine production.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” The research identified unique metabolic activities in immune cells associated with hair loss in Alopecia Areata.
March 2016 in “The Korean Society of Beauty and Art” This study evaluated the effects of an MSG-based hair hardener on hair treated with perms, focusing on hair elasticity and retention. The hair hardener was found to be stable and safe, with no physical or color changes at room temperature and no allergic reactions in 20 participants. Hair treated with the hardener showed increased thickness, higher levels of total amino acids, L-glutamic acid, and cysteine, and changes in surface color (higher L* and a* values, lower b* value). SEM analysis revealed tidier hair cuticles, and tensile strength was greater in the experimental group. Additionally, wave efficiency after shampooing was higher in the experimental group compared to the control group.
73 citations,
June 2006 in “Animal genetics” The FGF5 gene determines hair length in dogs.
4 citations,
April 2010 in “International Journal of Cosmetic Science” Curved human hair has different structures on its convex and concave sides.
20 citations,
June 2013 in “Journal of Lipid Research” The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.
12 citations,
January 2013 in “Indian Journal of Dermatology” Monilethrix is a rare genetic hair disorder that's hard to treat.
January 2023 in “Odisha Journal of Psychiatry” Thorough patient interviews are crucial to identify self-inflicted hair loss.