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The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Finasteride and flutamide effectively reduce hirsutism in PCOS women, with flutamide also lowering hormone levels.

Bergamot may improve heart health, skin conditions, and mood, but more research is needed to confirm these benefits.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

The document concludes that treating PCOS requires a combination of drugs to manage reproductive and metabolic symptoms, with more research needed on combination therapies.

Treat genetic hair loss early with FDA-approved medications and consider hair transplantation.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

A male with aromatase deficiency improved bone health with estradiol treatment.

The study found that women with PCOS have more and larger ovarian follicles and differences in ovarian structure, but these features alone can't always diagnose PCOS.

Women with PCOS tend to have higher anxiety and depression levels compared to healthy women.

The conclusion is that accurately identifying the cause of high androgen levels in women with PCOS is crucial and requires specific tests.

The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.

Hairless mice lack fur due to a genetic mutation affecting skin response, not hormone issues.

Women with PCOS have a higher risk of diabetes, heart problems, certain cancers, and mental health issues, but early treatment can help manage these risks.

More PDCD4 is linked to obesity, insulin problems, and cell death in ovaries for those with polycystic ovary syndrome.

Many young Italian women have hyperandrogenic disorders like PCOS, which are linked to age, body weight, and insulin resistance.

New treatments for PCOS show promise, but no current medication treats all aspects of the condition.

Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.

Most dogs with alopecia had higher than normal levels of certain hormones, but hair loss might not always be linked to these hormone changes.

New treatments for immune disorders caused by FOXN1 deficiency are promising.

Over half of the adult women with acne in the study had higher than normal levels of male hormones, especially DHEA.

Doctors should know how to diagnose and treat PCOS, which often involves checking for high male hormone levels and using medications to manage symptoms.

FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.

Extramammary Paget disease can spread deeply into tissues, reaching up to 3.6 mm.

Brazilian women with PCOS and both menstrual irregularity and high male hormone levels have a higher chance of having metabolic syndrome.

Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.

APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.

Curcumin may improve blood sugar levels and cholesterol in people with PCOS, but more research is needed.

Skin organoids are a promising new model for studying human skin development and testing treatments.