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PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

Methotrexate effectively treated a 2-year-old's generalized pustular psoriasis without side effects.

Hormonal imbalances, often indicating conditions like PCOS, are common in women with hard-to-treat acne, and a treatment approach addressing these imbalances may be needed.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

Increasing ABC transporters in hair follicles may prevent chemotherapy-induced hair loss.

Early diagnosis and treatment are key to managing health risks in teens with PCOS.

Thyroid hormones affect skin texture, hair and nail growth, and can cause skin diseases related to thyroid problems.

The PCOS-specific questionnaire needs more work to fully measure quality of life in clinical trials.

Budesonide and N-acetylcysteine reduced tumors and alopecia in mice, regardless of FHIT gene status.

Different anti-androgen medications can help treat excessive hair growth, but the right choice depends on accurate diagnosis.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

Hormonal therapy is a treatment option for acne, the only medical treatment for hirsutism, and the most promising for androgenetic alopecia.

Acne severity in women may not be linked to increased male hormone indicators like excess body hair, menstrual irregularities, or hair loss.

Diabetes often causes various skin problems and complications.

ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.

Dermatologists should screen for and manage psychological issues in patients with skin conditions to improve their quality of life.

The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

An mFG score of 7 or higher indicates hirsutism in Filipino women, often linked to higher free testosterone levels.

Many young Australian women think they have PCOS, but only a few are diagnosed correctly, causing unnecessary worry.

The oral glucose tolerance test is effective in detecting abnormal glucose tolerance in Indian women with PCOS.

Stress can worsen skin conditions and affect mental health, so doctors should include stress management in skin treatment.

Acne severity in women with PCOS is linked to younger age, lower body weight, and more body hair, but not to hormone levels.

Birth control pills help treat skin and hair growth problems linked to high male hormone levels.

Most patients experienced hirsutism again after stopping hormone treatment, indicating long-term treatment is needed to maintain results.

Women with hyperandrogenic amenorrhea have similar bone density to healthy women but lower than androgenized women without amenorrhea, and high DHEAS levels might affect bone density.

A specific gene change plus an additional mutation in the same gene cause hereditary trichilemmal cysts.

Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.

Women with PCOS, especially those overweight, have higher levels of IL-18 in their endometrium, which may affect fertility.

Topical minoxidil helps treat female pattern hair loss, but more research needed for other treatments.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.