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Higher levels of unbound testosterone are linked to increased insulin resistance, especially in women with polycystic ovary syndrome.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

A simple screening method found that 6.3% of women in a semiurban area in Sri Lanka have polycystic ovary syndrome, with most showing menstrual irregularities.

Platelet-rich plasma might help with hair growth and skin conditions, but more research is needed to prove its effectiveness and safety.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.

Understanding the mouse hair cycle is crucial for cancer research.

New treatments targeting specific genes show promise for treating keratin disorders.

ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.

Lowering testosterone speeds up wound healing in male mice.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.

Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.

Scientists created stem cells that can grow hair and skin.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Different soft tissue fillers can cause various skin reactions; biodegradable fillers are safer and non-biodegradable ones like silicone can lead to long-term problems.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.

All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.