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    Glossary CYP3A4

    enzyme that metabolizes drugs and toxins in liver

    CYP3A4 is an enzyme found in the liver and intestines that plays a crucial role in metabolizing many drugs and toxins in the body. It helps break down substances so they can be more easily eliminated, and its activity can affect how well medications work and their potential side effects.

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    Research 30 of 257

    1. Effect of a Benign Prostatic Hyperplasia (BPH) Xenobiotic - Croton membranaceus Müll.Arg. Root Extract on CYP1A2, CYP3A4, CYP2D6, and GSTM1 Drug Metabolizing Enzymes in Rat Model 2020 · 1 citations
    2. SAT340 Matters Of The HAART - Ritonavir Induced CYP3A4 Inhibition of Intranasal Fluticasone Leading To Cushing’s Syndrome Journal of the Endocrine Society · 2023 · 1 citations
    3. A Simple Decision Tree Suited for Identification of Early Oral Drug Candidates With Likely Pharmacokinetic Nonlinearity by Intestinal CYP3A Saturation Journal of Pharmaceutical Sciences · 2020
    4. CYP3A5 Polymorphism in Circulating Tumor Cells Confers an Increased Disease-Free Survival in DLBCL Patients Treated with R-CHOP OncoTargets and Therapy · 2025
    5. A population pharmacokinetic model for individualized regimens of finasteride according to CYP3A5 genotype and liver function Journal of pharmaceutical investigation · 2023
    6. Pilot study: genetic distribution of AR, FGF5, SULT1A1 and CYP3A5 polymorphisms in male Mexican population with androgenetic alopecia. PubMed · 2022
    7. Cloning of a Functional Vitamin D Receptor from the Lamprey (Petromyzon marinus), an Ancient Vertebrate Lacking a Calcified Skeleton and Teeth Endocrinology · 2003 · 104 citations
    8. Relationship of Early-Onset Baldness to Prostate Cancer in African-American Men Cancer Epidemiology, Biomarkers & Prevention · 2013 · 21 citations
    9. Drug safety evaluation of exemestane Expert Opinion on Drug Safety · 2011 · 7 citations
    10. Drug interactions between common dermatological medications and the oral anti-COVID-19 agents nirmatrelvir-ritonavir and molnupiravir Annals Academy of Medicine Singapore · 2022 · 5 citations
    11. Single nucleotide polymorphisms associated with elevated alanine aminotransferase in patients receiving asunaprevir plus daclatasvir combination therapy for chronic hepatitis C PLOS ONE · 2019 · 2 citations
    12. High-resolution mass spectrometric investigation of the phase I and II metabolites of finasteride in pig plasma, urine and bile Xenobiotica · 2013 · 2 citations
    13. Iatrogenic Cushing Syndrome and Secondary Adrenal Insufficiency Due to an Interaction Between Fluticasone and Ritonavir Journal of the Endocrine Society · 2021 · 1 citations
    14. In vivo Pharmacokinetic Interactions of Finasteride and Identification of Novel Metabolites 2010 · 1 citations
    15. Identification of Metabolites for the Novel 5α‐Reductase Inhibitor Epristeride In Vitro and Its Potential Impact on Doping Testing Drug Testing and Analysis · 2025
    16. Arecaceae Elsevier eBooks · 2015
    17. Ferrous sulfate overdose Reactions Weekly · 2011
    18. Pharmacogenomic variation and chemotherapy-related toxicity profiles in pediatric patients with cancer in Tanzania: a cross-sectional study Frontiers in Pharmacology · 2026
    19. Cushing's syndrome due to pharmacological interaction in a cystic fibrosis patient Acta pædiatrica · 2002 · 37 citations
    20. Cushing's syndrome due to pharmacological interaction in a cystic fibrosis patient Acta pædiatrica · 2002 · 6 citations
    21. Hormone receptor positive, HER2 negative metastatic breast cancer: Impact of CDK4/6 inhibitors on the current treatment paradigm Asia-Pacific Journal of Clinical Oncology · 2018 · 4 citations
    22. Simvastatin-induced myoglobinuric acute kidney injury following ciclosporin treatment for alopecia universalis ˜The œYear book of dermatology · 2012
    23. Identification of human cytochrome P450 isozymes responsible for the in vitro oxidative metabolism of finasteride. PubMed · 1995 · 20 citations
    24. Interaction of antiretroviral medications with finasteride Journal of the International AIDS Society · 2012
    25. Effects of mitotane treatment on human steroid metabolism: implications for patient management Endocrine Connections · 2012 · 26 citations
    26. Docking-based workflow and ADME prediction of some compounds in Curcuma longa and Andrographis paniculata as polymerase PA-PB1 inhibitors of influenza A/H5N1 virus Journal of Research in Pharmacy · 2023 · 8 citations
    27. Hair Loss Induced by Lopinavir-Ritonavir Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy · 2007 · 7 citations
    28. Treatment of Delusional Infestation with Olanzapine Indian Journal of Psychological Medicine · 2012 · 3 citations
    29. ラット精巣におけるビタミンD 代謝関連遺伝子の発現解析 Institutional Repositories DataBase (IRDB) · 2025
    30. Teriflunomide in multiple sclerosis: an update Neurodegenerative disease management · 2016 · 20 citations