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    Did you mean CYP3A4?
    Glossary CYP3A4

    enzyme that metabolizes drugs and toxins in liver

    CYP3A4 is an enzyme found in the liver and intestines that plays a crucial role in metabolizing many drugs and toxins in the body. It helps break down substances so they can be more easily eliminated, and its activity can affect how well medications work and their potential side effects.

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    Research 30 of 395

    1. SAT340 Matters Of The HAART - Ritonavir Induced CYP3A4 Inhibition of Intranasal Fluticasone Leading To Cushing’s Syndrome Journal of the Endocrine Society · 2023 · 1 citations
    2. Effect of a Benign Prostatic Hyperplasia (BPH) Xenobiotic - Croton membranaceus Müll.Arg. Root Extract on CYP1A2, CYP3A4, CYP2D6, and GSTM1 Drug Metabolizing Enzymes in Rat Model 2020 · 1 citations
    3. A Simple Decision Tree Suited for Identification of Early Oral Drug Candidates With Likely Pharmacokinetic Nonlinearity by Intestinal CYP3A Saturation Journal of Pharmaceutical Sciences · 2020
    4. CYP3A5 Polymorphism in Circulating Tumor Cells Confers an Increased Disease-Free Survival in DLBCL Patients Treated with R-CHOP OncoTargets and Therapy · 2025
    5. A population pharmacokinetic model for individualized regimens of finasteride according to CYP3A5 genotype and liver function Journal of pharmaceutical investigation · 2023
    6. Pilot study: genetic distribution of AR, FGF5, SULT1A1 and CYP3A5 polymorphisms in male Mexican population with androgenetic alopecia. PubMed · 2022
    7. Cloning of a Functional Vitamin D Receptor from the Lamprey (Petromyzon marinus), an Ancient Vertebrate Lacking a Calcified Skeleton and Teeth Endocrinology · 2003 · 104 citations
    8. Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models Archives of Toxicology · 2018 · 38 citations
    9. Cushing's syndrome due to pharmacological interaction in a cystic fibrosis patient Acta pædiatrica · 2002 · 37 citations
    10. Relationship of Early-Onset Baldness to Prostate Cancer in African-American Men Cancer Epidemiology, Biomarkers & Prevention · 2013 · 21 citations
    11. Drug safety evaluation of exemestane Expert Opinion on Drug Safety · 2011 · 7 citations
    12. Cushing's syndrome due to pharmacological interaction in a cystic fibrosis patient Acta pædiatrica · 2002 · 6 citations
    13. Drug interactions between common dermatological medications and the oral anti-COVID-19 agents nirmatrelvir-ritonavir and molnupiravir Annals Academy of Medicine Singapore · 2022 · 5 citations
    14. Hormone receptor positive, HER2 negative metastatic breast cancer: Impact of CDK4/6 inhibitors on the current treatment paradigm Asia-Pacific Journal of Clinical Oncology · 2018 · 4 citations
    15. Single nucleotide polymorphisms associated with elevated alanine aminotransferase in patients receiving asunaprevir plus daclatasvir combination therapy for chronic hepatitis C PLOS ONE · 2019 · 2 citations
    16. High-resolution mass spectrometric investigation of the phase I and II metabolites of finasteride in pig plasma, urine and bile Xenobiotica · 2013 · 2 citations
    17. Iatrogenic Cushing Syndrome and Secondary Adrenal Insufficiency Due to an Interaction Between Fluticasone and Ritonavir Journal of the Endocrine Society · 2021 · 1 citations
    18. In vivo Pharmacokinetic Interactions of Finasteride and Identification of Novel Metabolites 2010 · 1 citations
    19. Pharmacogenomic variation and chemotherapy-related toxicity profiles in pediatric patients with cancer in Tanzania: a cross-sectional study Frontiers in Pharmacology · 2026
    20. Identification of Metabolites for the Novel 5α‐Reductase Inhibitor Epristeride In Vitro and Its Potential Impact on Doping Testing Drug Testing and Analysis · 2025
    21. Arecaceae Elsevier eBooks · 2015
    22. Ferrous sulfate overdose Reactions Weekly · 2011
    23. Studying the genetic predisposing factors in the pathogenesis of acne vulgaris Human Immunology · 2011 · 39 citations
    24. Hepatotoxicity with low- and ultralow-dose flutamide: a surveillance study on 203 hyperandrogenic young females Fertility and Sterility · 2012 · 29 citations
    25. Clinical-exome sequencing unveils the genetic landscape of polycystic ovarian syndrome (PCOS) focusing on lean and obese phenotypes: implications for cost-effective diagnosis and personalized treatment Scientific Reports · 2024 · 13 citations
    26. Does maternal exposure to artificial food coloring additives increase oxidative stress in the skin of rats? Human & Experimental Toxicology · 2016 · 13 citations
    27. Heterozygous 21‐hydroxylasedeficiency as a cause of hyperandrogenism Journal der Deutschen Dermatologischen Gesellschaft · 2012 · 1 citations
    28. Single-cell analysis of 2,3,7,8-tetrachlorodibenzo- <i>p</i> -dioxin (TCDD)-treated murine skin demonstrates that sebaceous gland differentiation precedes <i>Ahr</i> -dependent seboatrophy with elevated expression of infundibular <i>Blimp1</i> bioRxiv (Cold Spring Harbor Laboratory) · 2026
    29. Clinical-Exome Sequencing Unveils the Genetic Landscape of Polycystic Ovarian Syndrome (PCOS) Focusing on Lean and Obese Phenotypes: Implications for Cost-Effective Diagnosis and Personalized Treatment Research Square (Research Square) · 2024
    30. 615 Evaluation of a combination of botanical extracts designed to protect hair and scalp from air pollutants: in vitro and clinical studies Journal of Investigative Dermatology · 2019