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Sustained-release sodium valproate is effective in treating epilepsy, with some side effects influenced by genetics.

Genetic variants can affect valproic acid's effectiveness, side effects, and levels in epilepsy treatment.

Some blood-thinning medications can increase the risk of bleeding, and certain factors like genetics and other health conditions affect their safety and effectiveness.

Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The Rotterdam Study aims to understand various diseases in older adults.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

The Rotterdam Study investigates diseases in older adults and has produced many research findings.

New information shows Valproate may protect the brain and reduce breathing failure risk but can cause liver damage and other side effects, with genetics affecting dosage needs.

Terbinafine is more effective than itraconazole for toenail fungus, especially in older patients, and debridement improves its effectiveness.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Zaleya pentandra extracts, especially acetone, may be useful for new medicines and food industry applications.

Ruxolitinib significantly improves multiple autoimmune conditions in APS-1 patients.

The decision tree can predict drug absorption issues with good accuracy but needs more validation and adjustments for other factors.

Certain herbal compounds, especially from bitter melon, can inhibit cancer growth and promote hair growth by blocking PAK1.

Teriflunomide effectively reduces relapses and disability in MS and has a manageable safety profile.

Monitoring for adverse effects in clinical treatments is crucial.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Isotretinoin therapy for acne can cause many reversible side effects, mainly mild skin conditions, and patient understanding of these effects can improve treatment adherence.

Transgender and gender-diverse adults on hormone therapy often face drug-hormone interactions, especially with multiple psychotropic medications.

Finasteride dosages should be adjusted based on CYP3A5 genotype and liver function to avoid side effects.

Ketoconazole increases finasteride's effectiveness and lifespan in the body.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Red ginseng may improve immunity, fatigue, memory, blood circulation, and menopausal symptoms, and is generally safe to consume.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Shell ginger contains kavalactones that promote hair growth and have anti-cancer, anti-inflammatory, and anti-obesity effects.

Terbinafine is the most effective medicine for fungal nail infections, especially for diabetics and those with weak immune systems.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Centipeda minima extract helps hair grow by activating important growth signals and could be a promising hair loss treatment.

Finasteride metabolites found in pigs match human studies, making pigs a valid model for human drug research.