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Finasteride doesn't affect omeprazole metabolism in Japanese people.

The decision tree can predict drug absorption issues with good accuracy but needs more validation and adjustments for other factors.

Teriflunomide effectively reduces relapses and disability in MS and has a manageable safety profile.

Leflunomide is effective for rheumatoid arthritis but has significant side effects.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

New topical antifungals and delivery systems are improving treatment for fungal skin infections, but patient education and prevention are key.

Voriconazole can cause serious side effects, especially in long-term use.

Red ginseng may improve immunity, fatigue, memory, blood circulation, and menopausal symptoms, and is generally safe to consume.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Tofacitinib citrate is effective for moderate-to-severe chronic plaque psoriasis but has safety concerns at higher doses.

Centipeda minima extract helps hair grow by activating important growth signals and could be a promising hair loss treatment.

Skin problems from transplant drugs are common and need careful management in organ transplant patients.

The severity of symptoms in nonclassical congenital adrenal hyperplasia is not determined by CYP21A2 gene variations.

Finasteride affects UGT1A4 enzyme, but not enough to cause issues when combined with other drugs.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Finasteride 5-mg oral disintegrating tablets and standard tablets are bioequivalent in healthy adult male Han Chinese volunteers.

Certain Dibenzo derivatives may help treat prostate cancer.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Targeted therapies for lung cancer are effective but require careful management of side effects to benefit patients.

Finasteride metabolites found in pigs match human studies, making pigs a valid model for human drug research.

Zaleya pentandra extracts, especially acetone, may be useful for new medicines and food industry applications.

Terbinafine is the most effective medicine for fungal nail infections, especially for diabetics and those with weak immune systems.

The model and estimator can predict drug exposure in kidney transplant patients well.

Terbinafine is more effective than itraconazole for toenail fungus, especially in older patients, and debridement improves its effectiveness.

The traditional herbal formulas Yongdamsagan-Tang and Paljung-san, along with the drug finasteride, can reduce inflammation and may work together without affecting each other's effectiveness against benign prostatic hyperplasia.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.