Search

everythinglearnresearchcommunity

for

Search:↓

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.

Certain drugs that block specific enzymes can help treat prostate diseases.

No link found between aromatase gene and female hair loss.

1α,25-dihydroxyvitamin D3 directly affects cartilage growth and development.

Two gene variations, rs6493497 and rs7176005, may be linked to female hair loss in Chinese people.

No significant link was found between the studied genes and female hair loss in the Polish population.

Oral contraceptive use may increase the risk of frontal fibrosing alopecia in women with a specific CYP1B1 gene variant.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

Aromatase gene variation may increase female hair loss risk.

Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.

Mice without Vitamin D receptors have hair growth problems because of issues in the hedgehog signaling pathway.

Genes and hormones cause hair loss, with four genes contributing equally.

The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

A male with aromatase deficiency improved bone health with estradiol treatment.

The right amount of retinoic acid is essential for normal hair growth and development.

New treatments for PCOS focus on insulin resistance and reducing testosterone levels, along with traditional hormone therapies.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

Low and ultralow doses of flutamide can cause liver damage in young women with high androgen levels, regardless of dose or birth control use, with higher risk for those with higher BMI and liver enzyme levels before treatment.

Hair loss involves immune responses, inflammation, and disrupted signaling pathways.

The scraggly mutation causes hair loss and skin defects in mice.

The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

The R343H mutation in the VDR gene causes vitamin D-resistant rickets with alopecia by impairing specific gene activity.