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Certain genetic variants are linked to frontal fibrosing alopecia in Spanish patients.

Oral contraceptive use may increase the risk of frontal fibrosing alopecia in women with a specific CYP1B1 gene variant.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

Astilbin can potentially calm overactive immune responses, like in Type 1 Diabetes, by suppressing certain cell activities and reducing inflammation.

Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

YAP and TAZ proteins are necessary for the development of two types of skin cancer.

Hair loss in balding individuals is linked to changes in specific hair growth-related genes.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Prolactin may affect hair growth differently based on gender and scalp area.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Frontal Fibrosing Alopecia's cause is unclear, affects mainly postmenopausal women, and current treatments focus on stopping hair loss rather than regrowth.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

Finasteride improves heart function and repairs damage after heart attack in mice.

Asian patients with Frontal Fibrosing Alopecia often lose eyebrow hair and respond well to combined antiandrogen or antimalarial and topical treatments.

Blackcurrant extract may help reduce hair loss by promoting stem cell activity in hair follicles.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.

Porphyra-334 may help reduce wrinkles and promote hair growth.

Si Jun Zi Tang may slow aging by affecting specific cell signaling pathways.

Spin traps like PBN could protect skin from pollution and sunlight in cosmetics but need more research for safe use.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Genetic testing can help diagnose skin conditions but needs more research for full effectiveness.

Effective PCOS treatments require targeting specific signaling pathways.

Melatonin helps regulate sleep and may aid in treating various health issues.

The study concluded that similar pathways regulate hair growth in dogs and mice, and these pathways are disrupted in dogs with Alopecia X, affecting stem cells and hormone metabolism.