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Men's and women's pattern hair loss progress differently, with men showing more hair thinning and women having more widespread hair loss.

Certain genes and X chromosome patterns may significantly contribute to the development of hair loss.

FGF5 gene mutations cause unusually long eyelashes by affecting hair growth regulation.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

Hormones like testosterone and estrogen significantly affect hair growth and structure.

Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.

PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.

Increased FGFR2b signaling, influenced by androgens, plays a role in causing acne.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Testosterone is linked to cardiovascular risk factors and stroke, but its exact role is unclear.

Androgens increase muscle mass by promoting myoblast growth through ornithine decarboxylase.

Female pattern hair loss is caused by multiple factors and while treatments like topical minoxidil, hormone therapy, and low-level light therapy can help, none can fully cure it.

PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.

Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.

The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).

OCT4 helps granulosa cell growth in early-stage follicles, and FSH increases OCT4 through specific pathways.

Female pattern hair loss has multiple causes and treatments, with new therapies showing promise.

Low-dose oral minoxidil effectively reduces hair loss in women with female pattern hair loss.

Letrozole reduces seizures but not brain damage in mice.

Prostate cancer can progress even with low testosterone due to internal hormone production in the tumor.

High levels of male hormones and irregular periods best predict how well PCOS patients will respond to metformin treatment.

Pediatric endocrinologists should provide early fertility counseling and preservation options to young patients at risk of infertility.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Omega-6 fats in certain cells boost male hormone production.

Different genes are active in dogs' hair growth and skin, similar to humans, which helps understand dog skin and hair diseases and can relate to human conditions.

Androgen use may increase the risk of stroke, but more research is needed.

Eyelid cells share signaling components but differ in pathway activity.