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      research Pharmacological basis for clinical use of antiandrogens

      24 citations , July 1983 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry”
      This article reviews the discovery and various physiological effects of cyproterone acetate, reporting its established indications for several androgen-driven conditions but providing no new clinical data.
      Managing Cutaneous Manifestations of Hyperandrogenic Disorders

      research Managing Cutaneous Manifestations of Hyperandrogenic Disorders

      22 citations , January 2002 in “Treatments in endocrinology”
      This review examines the role of androgens in cutaneous disorders and the potential therapeutic effects of different oral contraceptives, noting variations in individual responses and the influence of genetic and local factors but reports no new clinical results.
      Alopecia: Unapproved Treatments or Indications

      research Alopecia: unapproved treatments or indications

      22 citations , March 2000 in “Clinics in Dermatology”
      This study developed a method using HPLC with UV-DAD and ESI-MS detection to identify prohibited substances like minoxidil and hormones in cosmetic products advertised online for hair loss and skin conditions.
      Interventions for Female Pattern Hair Loss

      research Interventions for female pattern hair loss

      21 citations , May 2016 in “The Cochrane library”
      This review found that while topical minoxidil is effective for treating female pattern hair loss, finasteride showed no more effectiveness than placebo, and low-level laser therapy increased hair count but with inconsistent results.
      Antiandrogen Therapy for Skin and Hair Disease

      research Antiandrogen Therapy for Skin and Hair Disease

      20 citations , April 2006 in “Dermatologic Clinics”
      This review discusses the role of androgen hormones in skin and hair conditions and highlights the potential of antiandrogen therapies in dermatology, reporting no new results.
      Current Aspects of Antiandrogen Therapy in Women

      research Current Aspects of Antiandrogen Therapy in Women

      20 citations , January 1999 in “Current Pharmaceutical Design”
      This study reports that various antiandrogen therapies, including spironolactone and finasteride, effectively address hirsutism, acne, androgenic alopecia, and ovulatory dysfunction in hyperandrogenic women and are generally well tolerated.
      Adrenal 21-Hydroxylase Gene Mutations in Slovenian Hyperandrogenic Women: Evaluation of Corticotrophin Stimulation and HLA Polymorphisms in Screening for Carrier Status

      research Adrenal 21-hydroxylase gene mutations in Slovenian hyperandrogenic women: evaluation of corticotrophin stimulation and HLA polymorphisms in screening for carrier status

      19 citations , August 1999 in “European journal of endocrinology”
      This study concluded that neither basal nor ACTH-stimulated 17-OHP concentrations effectively indicate carrier status for 21-hydroxylase deficiency among Slovenian hyperandrogenic women, recommending molecular analysis of the CYP21 gene for reliable screening.
      Clinical Updates in Hair

      research CLINICAL UPDATES IN HAIR

      19 citations , January 1997 in “Dermatologic Clinics”
      This chapter reviews various antiandrogens and androgen inhibitors, detailing their mechanisms, uses, and side effects, with a focus on spironolactone, finasteride, dutasteride, and oral contraceptives.
      Treatment of Female Androgenetic Alopecia With Cimetidine

      research Treatment of Female Androgenetic Alopecia With Cimetidine

      19 citations , March 1987 in “International Journal of Dermatology”
      This study reports that cimetidine treatment resulted in good to excellent hair regrowth in 70% of the small group of women with androgenetic alopecia, with no major side effects observed.
      Medical Treatment of Hirsutism in Women

      research Medical Treatment of Hirsutism in Women

      18 citations , June 2010 in “Current medicinal chemistry”
      This review discusses current treatment options for hirsutism, emphasizing the importance of combining therapies for better outcomes, but reports no new clinical findings.
      Spironolactone in the Treatment of Hirsutism

      research Spironolactone in the Treatment of Hirsutism

      17 citations , January 1986 in “Acta obstetricia et gynecologica Scandinavica”
      In this study, spironolactone treatment reduced hair growth in 17 out of 30 patients with hirsutism, but was less effective compared to cyproterone acetate–estrogen therapy.

      research Objective Assessment of Treatment Response in Hirsutism

      16 citations , November 2008 in “Hormone research”
      In this study, cyproterone acetate treatment in hirsute women resulted in a 19% reduction in hair growth rate and a 33% improvement in physician-rated hirsutism scores.
      Therapeutic Options in Polycystic Ovary Syndrome

      research Therapeutic options in the polycystic ovary syndrome

      16 citations , January 2007 in “Journal of Obstetrics and Gynaecology”
      This article provides a comprehensive overview of polycystic ovary syndrome, its diagnosis, complications, and symptom-focused management options, but does not present new clinical findings.
      Oral Contraceptives as Anti-Androgenic Treatment of Acne

      research Oral Contraceptives as Anti-Androgenic Treatment of Acne

      16 citations , July 2002 in “JOGC/Journal of obstetrics and gynaecology Canada”
      This review discusses treatments for female acne, highlighting the effectiveness of low-dose oral contraceptives and noting their similar side effects to placebo; it reports no new clinical results.

      research Androgen binding to cytosol and nuclei of hamster sebaceous glands

      16 citations , February 1978 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry”
      This study found that hamster sebaceous glands have high affinity binding sites for dihydrotestosterone, with competition from other steroids indicating specific binding characteristics.
      Hirsutism II: Treatment

      research Hirsutes II: Treatment

      15 citations , August 1998 in “Australasian journal of dermatology”
      This review discusses various treatments for hirsutism, including cosmetic techniques, anti-androgens like spironolactone, and new drugs such as finasteride and flutamide, but it reports no new clinical results.

      research The use of hormonal agents in the treatment of acne

      14 citations , June 2016 in “Seminars in Cutaneous Medicine and Surgery”
      This review examines hormonal therapies for acne in females, noting their effectiveness and encouraging further study and use to reduce antibiotic reliance, but it reports no new results.

      research Screening for Anti-inflammatory Activities in Extracts from Korean Herb Medicines

      14 citations , March 2014 in “Journal of the Society of Cosmetic Scientists of Korea”
      This study suggests that ethanol extracts from ten selected Korean herb medicines reduced inflammatory markers in a cell model and did not cause skin irritation in human testing, indicating potential cosmetic use for irritation prevention.
      A Review of Hormonal Therapy for Female Pattern (Androgenic) Alopecia

      research A review of hormonal therapy for female pattern (androgenic) alopecia

      14 citations , January 2008 in “Dermatology Online Journal”
      This review discusses the use of anti-hormonal therapies for female androgenetic alopecia and notes that while some treatments show promise, larger controlled studies are needed to define their roles and effectiveness.

      research Scraggly, a new hair loss mutation on mouse Chromosome 19

      14 citations , September 1999 in “Mammalian genome”
      In this study, researchers generated a mouse mutation called scraggly, related to hair and skin defects, and mapped it to a genetic location on mouse Chromosome 19 distinct from similar mutations.