42 citations,
March 2006 in “Drug Discovery Today: Therapeutic Strategies” The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
41 citations,
July 2015 in “Current Drug Discovery Technologies” Some plants may help with hair growth and have fewer side effects than synthetic drugs, but more research is needed to confirm their effectiveness.
23 citations,
February 2015 in “International Journal of Molecular Sciences” Colchicine can inhibit hair growth by affecting cell activity and protein expression in hair follicles.
29 citations,
December 2016 in “The EMBO Journal” Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.
212 citations,
September 2015 in “Journal of Investigative Dermatology” The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.
165 citations,
June 2007 in “European Journal of Cell Biology” Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
56 citations,
November 2010 in “Pigment Cell & Melanoma Research” Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.
16 citations,
December 2006 in “Expert Review of Dermatology” Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.
5 citations,
January 2017 in “Laboratory Animal Research” Gold thread implantation may help hair grow in humans and mice.
4 citations,
December 2017 in “International journal of research in ayurveda and pharmacy” The dodder plant has anti-inflammatory, antimicrobial properties, and may promote hair growth.
January 2012 in “Elsevier eBooks” New treatments for skin and hair repair show promise, but further improvements are needed.
2 citations,
March 2022 in “Applied sciences” Lespedeza bicolor extract promotes hair growth and increases hair follicle cell growth, potentially making it a better treatment than minoxidil.
August 2021 in “International Journal of Research in Dermatology” Amarantha hair oil contains β-sitosterol, which helps promote hair growth.
January 2020 in “Indian Journal of Pharmaceutical Sciences” Natural products show promise for new hair loss treatments.
56 citations,
March 2015 in “Journal of Investigative Dermatology” Healthy mitochondria in skin cells are essential for proper hair growth and skin cell interaction in mice.
January 2022 in “Springer eBooks” Fibroblast growth factors are crucial for hair follicle development and regeneration.
4 citations,
July 2020 in “BMC Complementary Medicine and Therapies” Human placenta helps hair grow back after chemotherapy by blocking cell death and increasing hair follicle growth.
48 citations,
February 2017 in “Journal of Cosmetic Dermatology” The conclusion is to use scalp cooling, gentle hair care, and treatments like minoxidil for managing hair loss from chemotherapy, and stresses the need for more research and collaboration in this area.
33 citations,
September 2012 in “Australasian Journal of Dermatology” Chemotherapy can cause hair changes similar to alopecia areata, which might lead to misdiagnosis.
3 citations,
June 2023 in “Medicines” Some antiseizure medications can cause reversible hair loss, with valproate, lamotrigine, and carbamazepine being the most common.
37 citations,
April 2010 in “FEBS Letters” The study concludes that the EDA2R gene is activated by p53 during chemotherapy but is not necessary for chemotherapy-induced hair loss.
31 citations,
August 2021 in “Stem Cell Research & Therapy” The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
11 citations,
June 2012 in “Archives of Dermatological Research” L-cystine and vitamin B6 at high doses prevented hair loss in mice treated with a chemotherapy drug.
19 citations,
July 2015 in “Journal of Ginseng Research” Korean Red Ginseng may protect against hair loss caused by chemotherapy.
52 citations,
May 2011 in “APOPTOSIS” Hydroxyl radicals cause hair follicle cell death during chemotherapy by reducing Bcl-2 protein levels.
172 citations,
November 1983 in “Journal of The American Academy of Dermatology” Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.
9 citations,
July 2014 in “Experimental Dermatology” PTHRP agonists can stimulate hair growth, especially in damaged follicles, while antagonists may initially increase growth but ultimately inhibit it.
153 citations,
January 2001 in “Science” Using CDK inhibitors on rats showed a reduction in chemotherapy-caused hair loss, but later experiments could not repeat these results.
3 citations,
May 1980 in “American Journal of Nursing” Scalp tourniquets did not significantly prevent hair loss from chemotherapy.
2 citations,
May 2018 in “Australasian Journal of Dermatology” Some patients' hair grew back black and white after chemotherapy.