June 2023 in “Journal of cosmetic medicine” Hair follicle stem cells and mitochondria are key for hair growth, and targeting their activity could lead to new hair loss treatments.
January 2019 in “Advances in stem cells and their niches” Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
January 2012 in “Else Kröner-Fresenius Symposia” Maintaining DNA integrity in stem cells is crucial to prevent aging and cancer.
184 citations,
November 2014 in “Developmental Cell” Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.
43 citations,
December 2008 in “Molecular biology of the cell” Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.
28 citations,
January 2013 in “Stem cells” Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.
22 citations,
June 2013 in “International journal of molecular sciences” Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.
21 citations,
July 2006 in “Veterinary dermatology” CD34 marks potential stem cells in dog hair follicles.
19 citations,
July 2011 in “Microscopy and Microanalysis” The hair follicle bulge is an important area for adult stem cells involved in hair growth and repair, with potential for medical use needing more research.
13 citations,
December 2014 in “Stem Cells” Hair and skin can regenerate without bulge stem cells due to other compensating cells.
5 citations,
March 2020 in “Cell and Tissue Banking” Injected cells show potential for hair growth.
2 citations,
May 2023 in “Frontiers in immunology” Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.
January 2015 in “Journal of Cytology and Histology” Hair loss in Androgenetic Alopecia is not caused by damage to follicular stem cells.
232 citations,
October 2015 in “International journal of molecular sciences” Stem cells are crucial for skin repair and new treatments for chronic wounds.
85 citations,
September 2013 in “International Journal of Molecular Sciences” Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.
69 citations,
April 2019 in “Biomedicines” PRP and HF-MSCs treatment improves hair growth, thickness, and density in androgenetic alopecia.
65 citations,
June 2020 in “Stem Cell Research & Therapy” Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.
62 citations,
April 2009 in “British Journal of Dermatology” Epidermal stem cells could lead to new treatments for skin and hair disorders.
46 citations,
June 2015 in “Journal of Investigative Dermatology” Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.
41 citations,
December 2018 in “Experimental Dermatology” Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.
35 citations,
July 2018 in “Cell Reports” The study found that a specific area of the hair follicle helps start hair growth by reducing the blocking effects on certain cells and controlling growth signals.
30 citations,
April 2013 in “Journal of Investigative Dermatology” Radiation mainly affects keratinocyte stem cells, not melanocyte stem cells, causing hair to gray.
29 citations,
July 2014 in “PloS one” Meis1 is crucial for skin health and tumor development.
26 citations,
July 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects” The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.
23 citations,
August 2018 in “Facial Plastic Surgery Clinics of North America” Using defensins to activate stem cells may improve skin aging signs without causing inflammation.
14 citations,
July 2019 in “Experimental and Molecular Medicine” Nanog gene boosts stem cells, helps hair growth, and may treat hair loss.
10 citations,
January 2018 in “Organogenesis” Porcine acellular dermal matrix treatment helps wounds heal faster and reduces scarring by affecting Jag1 in skin stem cells.
9 citations,
March 2013 in “Expert opinion on biological therapy” Epidermal stem cells have potential for personalized regenerative medicine but need careful handling to avoid cancer.
6 citations,
July 2013 in “Molecular Imaging” The technique allowed noninvasive tracking of hair stem cell survival and growth, showing potential for hair loss research.
4 citations,
January 2020 in “Cells” The research found that the gene activity in mouse skin stem cells changes significantly as they age.