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    Research 361–390 of 637

    1. Identification of dkk4 as a target of Eda-A1/Edar pathway reveals an unexpected role of ectodysplasin as inhibitor of Wnt signalling in ectodermal placodes Developmental biology · 2008 · 117 citations
    2. Forsythiae Fructus: A Review on its Phytochemistry, Quality Control, Pharmacology and Pharmacokinetics Molecules · 2017 · 110 citations
    3. WNT10A mutation causes ectodermal dysplasia by impairing progenitor cell proliferation and KLF4-mediated differentiation Nature Communications · 2017 · 96 citations
    4. The Wnt inhibitor, Dickkopf 4, is induced by canonical Wnt signaling during ectodermal appendage morphogenesis Developmental biology · 2007 · 96 citations
    5. Wnt/β‐catenin pathway in tissue injury: roles in pathology and therapeutic opportunities for regeneration The FASEB Journal · 2016 · 94 citations
    6. A Meeting of Two Chronobiological Systems: Circadian Proteins Period1 and BMAL1 Modulate the Human Hair Cycle Clock Journal of Investigative Dermatology · 2013 · 92 citations
    7. NEDD4 and NEDD4L regulate Wnt signalling and intestinal stem cell priming by degrading LGR5 receptor The EMBO Journal · 2019 · 91 citations
    8. The role of PPAR<i>γ</i>-mediated signalling in skin biology and pathology: new targets and opportunities for clinical dermatology Experimental Dermatology · 2015 · 84 citations
    9. Wedelolactone, a medicinal plant-derived coumestan, induces caspase-dependent apoptosis in prostate cancer cells via downregulation of PKCε without inhibiting Akt International Journal of Oncology · 2012 · 83 citations
    10. Epidermal patterning and induction of different hair types during mouse embryonic development Birth defects research · 2009 · 81 citations
    11. Hair follicles’ transit-amplifying cells govern concurrent dermal adipocyte production through Sonic Hedgehog Genes & Development · 2016 · 75 citations
    12. Targeting Wnt/β-catenin signaling and its interplay with TGF-β and Notch signaling pathways for the treatment of chronic wounds Cell Communication and Signaling · 2024 · 74 citations
    13. Roles of the Hedgehog Signaling Pathway in Epidermal and Hair Follicle Development, Homeostasis, and Cancer Journal of developmental biology · 2017 · 72 citations
    14. Effect of IGF-I on Hair Growth Is Related to the Anti-Apoptotic Effect of IGF-I and Up-Regulation of PDGF-A and PDGF-B Annals of Dermatology · 2012 · 72 citations
    15. Anabolic androgenic steroids and carcinogenicity focusing on Leydig cell: a literature review Oncotarget · 2018 · 65 citations
    16. Preclinical Pharmacology, Antitumor Activity, and Development of Pharmacodynamic Markers for the Novel, Potent AKT Inhibitor CCT128930 Molecular cancer therapeutics · 2011 · 65 citations
    17. Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/– mice Journal of Clinical Investigation · 2004 · 65 citations
    18. Human Induced Pluripotent Stem Cell–Derived Ectodermal Precursor Cells Contribute to Hair Follicle Morphogenesis In Vivo 2013 · 64 citations
    19. Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/– mice Journal of Clinical Investigation · 2004 · 64 citations
    20. Receptor activator of NF-κB (RANK) stimulates the proliferation of epithelial cells of the epidermo-pilosebaceous unit Proceedings of the National Academy of Sciences of the United States of America · 2011 · 60 citations
    21. DKK1 Mediated Inhibition of Wnt Signaling in Postnatal Mice Leads to Loss of TEC Progenitors and Thymic Degeneration PLOS ONE · 2010 · 56 citations
    22. The Vitamin D Receptor as Tumor Suppressor in Skin Advances in experimental medicine and biology · 2020 · 55 citations
    23. Involvement of Wnt, Eda and Shh at defined stages of sweat gland development Development · 2014 · 55 citations
    24. Regulation of stem cell function by protein ubiquitylation EMBO Reports · 2014 · 55 citations
    25. Myricetin: A Significant Emphasis on Its Anticancer Potential via the Modulation of Inflammation and Signal Transduction Pathways International Journal of Molecular Sciences · 2023 · 54 citations
    26. The evolutionary impact of androgen levels on prostate cancer in a multi-scale mathematical model Biology direct · 2010 · 50 citations
    27. Plasma Dermatology: Skin Therapy Using Cold Atmospheric Plasma Frontiers in Oncology · 2022 · 46 citations
    28. The potential application of natural products in cutaneous wound healing: A review of preclinical evidence Frontiers in Pharmacology · 2022 · 45 citations
    29. Alleviation of Multidrug Resistance by Flavonoid and Non-Flavonoid Compounds in Breast, Lung, Colorectal and Prostate Cancer International Journal of Molecular Sciences · 2020 · 45 citations
    30. Bone Morphogenetic Protein Antagonist Noggin Promotes Skin Tumorigenesis via Stimulation of the Wnt and Shh Signaling Pathways American Journal Of Pathology · 2009 · 45 citations