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This study found that PRC2 plays a non-instructive role in adult hair follicle stem cells, with its loss not affecting quiescence or cell identity, despite upregulation of genes linked to activation.

This study identified distinct gene expression patterns in wool follicle bulbs that may play important roles in wool follicle cycling and regeneration in sheep.

This review discusses the interplay between signaling/transcription factor-mediated and epigenetic mechanisms in skin development and regeneration, highlighting the need for further exploration of epigenome reorganization in these processes.

This study found that the protein CCN2 in dermal papilla cells is a physiologically relevant suppressor of hair follicle formation by destabilizing β-catenin, which may help maintain stem cell quiescence.

This study reported that apremilast treatment did not lead to sustained improvement in SALT scores for most patients with extensive and treatment-resistant alopecia areata.

In this study, the authors explored the role of Lgr5+ hair follicle stem cells and their regulation through the Wnt/-catenin pathway, highlighting how precise modulation of this pathway is crucial for treating hair loss safely and effectively.

This review summarizes advancements in biomedical engineering for hair follicle regeneration, highlighting strategies like cell transplantation and tissue engineering to reconstruct hair follicles, and discusses both their technical limitations and potential future innovations in regenerative medicine.

This study found that a biomaterial gel made from human hair keratins facilitated nerve regeneration in an animal model, potentially matching the effectiveness of traditional autografts.

This review discusses recent advances in understanding hair follicle stem cell dynamics and interactions, but it reports no new experimental findings.

This review discusses the latest understanding of androgenetic alopecia, including stem cell niches in hair follicles, and highlights emerging treatments like growth factors and platelet-rich plasma without new clinical findings.

This study evaluated the efficacy of polyphenolic compounds for hair growth in adults with non-scarring alopecia and found that these interventions significantly improved hair density and total area hair count compared to controls, although results were not significantly different from minoxidil.

This review highlights recent advancements in nanotechnology-based approaches for treating androgenetic alopecia, focusing on enhancing drug delivery to hair follicles, controlled release, and follicular microenvironment modulation, while addressing safety, manufacturing, and regulatory challenges for clinical application.

This study reviews advancements in hair follicle regeneration, discussing the benefits and limitations of methods such as organ germ assembling, stem cell induction, and bioprinting, while highlighting the challenges of replicating embryonic signals and finding suitable cell sources for clinical applications.

This study reviewed various methods and techniques aimed at overcoming limitations in culturing human hair follicles, specifically focusing on restoring the inductivity of hair follicle cells for successful hair regeneration.

This review discusses factors influencing hair pigmentation and the etiology of canities, noting the lack of clarity in underlying mechanisms and calling for further research on treatment options.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

This study suggests that human and mouse hair follicle stem cells may support nerve repair and provide a practical source of stem cells for neurological therapies.

This review discusses recent advances in hair regeneration strategies, including mechanical stimulation and complementary therapies like MSC transplantation and platelet-rich plasma, and reports no new clinical results.

This article discusses the discovery of the first known menstruating rodent, the spiny mouse, and proposes that a significant increase in progesterone during the luteal phase is a unique feature of menstruating species, but reports no new experimental results.

This review discusses the diverse roles and characteristics of epidermal and dermal stem cells in skin regeneration and aging, highlighting their potential applications in regenerative medicine and reports no new clinical results.

This review discusses the distinct roles and surprising developmental flexibility of multiple somatic stem cell types in tissue maintenance and repair, reporting no new results but highlighting emerging questions about their regulation and origins.

This study found that composite skin constructs containing dermal papilla cells promoted better skin healing and hair regeneration in nude mice, highlighting their role in tissue-engineered skin for severe injuries.

This review discusses how immune mechanisms contribute to the regeneration and repair of epithelial tissues and highlights their potential role in both disease and therapeutic innovation; it reports no new clinical results.

This review provides a framework for diagnosing acquired scalp alopecias and discusses both non-scarring and scarring types, but reports no new clinical results.

Stretching skin increases a certain protein that attracts stem cells, helping skin regeneration.

This review introduces an integrated view of hair follicle behavior, highlighting a Yin Yang model of regulation and suggesting glycans as key elements in hair follicle growth control, without reporting new clinical findings.

This review discusses recent advances in understanding the molecular landscape of the dermal papilla, particularly focusing on Blimp1's role in hair follicle development and potential therapeutic targets for hair regeneration, but presents no new clinical results.

This study found that Wnt ligands from CD133-positive dermal papilla cells are essential for maintaining hair growth by supporting cell signaling between different hair follicle structures.

This study found that exosomes derived from bovine colostrum promoted hair growth in mice by activating the Wnt/β-catenin pathway, with effects similar to minoxidil but without adverse effects.

This review explores the potential for using exosomes in treating autoimmune skin diseases and promoting skin regeneration, highlighting current applications, delivery methods, and ongoing clinical trials while also identifying challenges and future research directions within dermatology.