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Finding functions for unknown GPCRs is hard but key for making new drugs.

Androgenetic alopecia is influenced by various factors and can be treated with medications, procedures, and non-drug methods.

Different light affects cell functions and can help treat skin conditions.

There are many treatments for common hair loss, but more trials are needed to decide which are best.

PSA can help diagnose high androgen levels in women.

Skin lesions in Carney complex are likely caused by a specific group of skin cells that promote pigment production due to a genetic mutation.

Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.

UV radiation may cause DNA changes in skin, certain UVB therapy helps psoriasis, a new gene mutation is linked to mild piebaldism, different immune cells affect psoriasis, a drug promotes hair growth, and some cancer drugs could treat skin barrier issues.

Botulinum toxin type A significantly reduces scalp psoriasis severity compared to placebo.

Skin problems are common in thyroid disorders, with dry skin in hypothyroidism and warm, soft skin in hyperthyroidism.

Eating high-glycemic and dairy foods can increase hormones that may cause acne and other health issues.

Aging causes hair to gray and thin, with the timing of graying varying by race, and factors like oxidative stress and genetics can lead to hair loss.

Hormones significantly affect skin health, with vitamin D playing a key role.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

Caffeine can potentially treat common hair loss by counteracting hair follicle shrinkage caused by hormones.

Treatments for hair loss include hormone modifiers, minoxidil, and hair transplant surgery.

CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

Allopregnanolone changes gene expression in glioblastoma cells.

Cirsium japonicum flower extract increases melanin production and could help treat depigmentation conditions.

Deoxycholic acid is FDA-approved for reducing submental fat, but its mechanisms are not fully understood.

Transplanted rat hair follicles grew hair and had increased but not fully restored nerve connections in mice.

Ganoderma lucidum extract may help treat stress-related hair loss.

Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.

PAD is common but often missed, needing lifestyle changes and medication for better outcomes.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

GPRC5D is linked to the formation of hair, nails, and certain tongue areas.

Early recognition and treatment of Peripheral Arterial Disease is crucial to improve survival and health outcomes.

Some treatments like pentoxifylline with topical corticosteroids might work for alopecia areata, but more research is needed to find the best one.

Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.