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Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.

Certain drugs are effective for skin conditions like psoriasis, vitiligo, and hair loss.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Polydeoxyribonucleotide (PDRN) may help lighten skin and treat hyperpigmentation.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

New treatments for Alopecia Areata, like JAK inhibitors, show promise for hair regrowth and are likely to change future treatment approaches.

Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.

Women with PCOS who have low SHBG are more likely to have low good cholesterol and metabolic syndrome.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Lithium therapy may cause skin problems like hidradenitis suppurativa and other side effects, which can improve after stopping the medication.

Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Female pattern hair loss diagnosed by scalp appearance, treated with combined therapies and targeted approaches.

Apremilast was not effective in treating moderate-to-severe alopecia areata.

Bee venom might be a good alternative treatment for various skin conditions because it has many healing properties.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

β-blockers can cause skin problems like psoriasis and vitiligo, and doctors should tell patients about these risks.