Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study reports that androgenetic alopecia patients exhibit reduced CK15 and tropoelastin expression and increased cellular senescence markers, indicating tissue damage in affected hair follicles and surrounding structures.

In this study, finasteride was found to worsen the cardiac effects but reduce the mutagenic effects of nandrolone in male Wistar rats.

This study found that a combination of systemic cyproterone acetate, ethinyl estradiol, and 5% topical minoxidil significantly improved hair growth and prevented further hair loss in women with female pattern hair loss over six months, with the treatment being well-tolerated.

Cyproterone and finasteride reduced hypersexuality but caused serious side effects.

This review discusses how androgens and cytokines may interact in androgenetic alopecia and reports no new results; the authors note the need for further research.

This article reviews potential factors contributing to hair loss in androgenetic alopecia beyond genetic predispositions and discusses current knowledge without presenting new clinical results.

Cyclosporin doesn't stop hair loss.

This study found that the new cytopurine/pentadecanoic glyceride topical solution significantly improved total hair count and reduced daily hair shedding in patients with androgenetic alopecia over 16 weeks, although other measures did not differ from placebo.

Cyproterone helps women with hair loss caused by genetics. More research is needed to confirm the best dose.

This study found that recombinant IFN α-2b injections in patients with acute post-transfusion hepatitis C can suppress viral RNA and lead to normalization of serum ALT, though long-term prevention of chronicity remains unclear.

In this study, finasteride was found to significantly reduce DHT levels and affect spermatogenic markers in rats, while DA-9401 co-treatment indicated potential ameliorative effects.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

This study found that intradermal adipocyte lineage cells in mice are necessary and sufficient to activate follicular stem cells, highlighting their role in regulating skin stem cell activity.

This study demonstrated that keratin is widely present in various epithelial cells, providing structural strength and potential insights into the origin of cell lines.

This article reviews the stages and regulation of the hair cycle, highlighting molecular regulators involved, but it does not present new research findings.

This article reviews the role of epithelial-mesenchymal interactions in hair follicle morphogenesis and the hair cycle, suggesting potential paths for developing treatments for hair growth disorders but providing no new clinical findings.

TNFα helps grow and maintain liver cells in 3D culture for a long time.

This study found that the hairless gene product (Hr) suppresses VDR-mediated gene activation by directly interacting with the vitamin D receptor, potentially affecting hair follicle function.

This article presents a comprehensive guide for classifying human hair follicle cycle stages in vivo using scalp xenografts on immunocompromised mice, offering valuable resources for researchers in the field.

In this study, researchers found that the number of dermal papilla cells in hair follicles determines hair size and shape in mice, suggesting potential avenues for addressing hair loss.

This study found that trichocytic cytokeratins, typically found in hair, are also present in nails, filiform papillae of the tongue, and the epithelial reticulum of the thymus.

This study found that keratin 17 and TNFα play interdependent roles in regulating hair follicle cycling, with TNFα required for the anagen–catagen transition and its ablation partially rescuing hair cycling defects in K17-null mice.

FGF18 helps keep hair in its resting phase, affecting hair growth cycles.

This review discusses the conserved molecular mechanisms controlling hair follicle development and cycling and suggests they may also apply to other ectodermal derivatives, like teeth and feathers, but it reports no new results.

This review discusses the development, regulation, and aging of the human hair follicle pigmentary system and suggests potential for reversing hair graying by manipulating follicle melanocytes in vitro, but reports no clinical results.

In this study, miR-31 was found to play a significant role in hair cycle regulation in mice by controlling key gene expressions involved in hair growth and differentiation.

This study found that cathepsin L deficiency in mice led to significant abnormalities in hair follicle development and cycling, including disrupted hair shaft outgrowth and premature hair growth phase entry.

In this study, researchers found that bulge cells in mouse hair follicles undergo transient proliferation during early anagen, indicating their role as follicular stem cells. However, another factor beyond dermal papilla proximity may be required to initiate a new anagen phase.

This review examines regenerative hair waves and complex hair cycle domains in transgenic mice, highlighting how these dynamic processes contribute to skin regeneration and the physiological regulation of organs, but reports no new experimental results.

This study found that T cytokeratins appear more gradually and with complex coexpression patterns in developing nail structures compared to the more abrupt transition in hair follicles.