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    Glossary CXXC-type zinc finger protein 5

    regulates gene expression by binding specific DNA sequences

    CXXC-type zinc finger protein 5 (CXXC5) is a protein that plays a role in regulating gene expression by binding to specific DNA sequences. It is involved in various cellular processes, including cell growth and differentiation, and has been linked to conditions like alopecia, where it can influence hair follicle development and cycling.

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    Research 30 of 33

    1. Inhibiting the cytosolic function of CXXC5 accelerates diabetic wound healing by enhancing angiogenesis and skin repair Experimental & Molecular Medicine · 2023 · 19 citations
    2. The Negative Regulator CXXC5: Making WNT Look a Little Less Dishevelled Journal of Investigative Dermatology · 2017 · 8 citations
    3. Signal integrator function of CXXC5 in Cancer Cell Communication and Signaling · 2025
    4. Review of Hair Follicle Dermal Papilla cells as <i>in vitro</i> screening model for hair growth International Journal of Cosmetic Science · 2018 · 76 citations
    5. Dermal niche signaling and epidermal stem cells Advances in stem cells and their niches · 2019
    6. Roles of <i>jumonji</i> and <i>jumonji</i> family genes in chromatin regulation and development Developmental Dynamics · 2006 · 178 citations
    7. Androgen modulation of Wnt/β-catenin signaling in androgenetic alopecia Archives of Dermatological Research · 2018 · 39 citations
    8. Characterization of Novel Cutaneous Human Papillomavirus Genotypes HPV-150 and HPV-151 PLoS ONE · 2011 · 20 citations
    9. CXXC5: A novel regulator and coordinator of TGF-β, BMP and Wnt signaling Journal of Cellular and Molecular Medicine · 2018 · 28 citations
    10. Targeting of CXXC5 by a Competing Peptide Stimulates Hair Regrowth and Wound-Induced Hair Neogenesis Journal of Investigative Dermatology · 2017 · 37 citations
    11. CXXC5 Mediates DHT-Induced Androgenetic Alopecia via PGD2 Cells · 2023
    12. Novel small molecules downregulate CDK1 expression and inhibit Wnt/β-catenin signaling in cutaneous squamous cell carcinoma by targeting its distinct tumor-specific cellular landscape Experimental & Molecular Medicine · 2025
    13. Lifestyle factors affecting the pathogenesis of androgenetic alopecia: a literature review Frontiers in Public Health · 2026
    14. Scarless wound healing: finding the right cells and signals Cell and Tissue Research · 2016 · 132 citations
    15. KY19382, a novel activator of Wnt/β‐catenin signalling, promotes hair regrowth and hair follicle neogenesis British Journal of Pharmacology · 2021 · 13 citations
    16. Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease Genes & Development · 2008 · 667 citations
    17. Pyruvate Kinase M2 Accelerates Cutaneous Wound Healing via Glycolysis and Wnt/β-Catenin Signaling Pharmaceutics · 2023 · 10 citations
    18. Scars or Regeneration?—Dermal Fibroblasts as Drivers of Diverse Skin Wound Responses International Journal of Molecular Sciences · 2020 · 123 citations
    19. KY19382 Accelerates Cutaneous Wound Healing via Activation of the Wnt/β-Catenin Signaling Pathway International Journal of Molecular Sciences · 2023 · 18 citations
    20. Delivery Strategies of siRNA Therapeutics for Hair Loss Therapy International Journal of Molecular Sciences · 2024 · 1 citations
    21. Isoxazole 9 (ISX9), a small molecule targeting Axin, activates Wnt/β‐catenin signalling and promotes hair regrowth British Journal of Pharmacology · 2023 · 11 citations
    22. Molecular Signaling Pathways in Wound-Induced Hair-Follicle Neogenesis Cells · 2025
    23. KY19382, a novel activator of Wnt/β-catenin signaling, promotes hair re-growth and hair follicle neogenesis 2020
    24. Double Knockdown of the Androgen Receptor Target Genes DKK1 and SFRP1 Does Not Potentiate the Hair Growth-Promoting Effect of SFRP1 Silencing in Healthy Human Hair Follicles Ex Vivo International Journal of Molecular Sciences · 2026
    25. Pathogenic Mechanisms and Mechanism‐Directed Therapies for Androgenetic Alopecia: Current Understanding and Future Directions Dermatologic Therapy · 2025
    26. Targeting Wnt/β-catenin signaling and its interplay with TGF-β and Notch signaling pathways for the treatment of chronic wounds Cell Communication and Signaling · 2024 · 74 citations
    27. Through the lens of hair follicle neogenesis, a new focus on mechanisms of skin regeneration after wounding Seminars in Cell & Developmental Biology · 2019 · 28 citations
    28. Whole blood transcriptome profiling identifies candidate genes associated with alopecia in male giant pandas (Ailuropoda melanoleuca) BMC Genomics · 2022 · 1 citations
    29. ISX9, a small molecule targeting Axin, activates Wnt/β-catenin signaling and promotes hair regrowth 2022
    30. Androgenetic alopecia: combing the hair follicle signaling pathways for new therapeutic targets and more effective treatment options Expert Opinion on Therapeutic Targets · 2019 · 19 citations