research CCL5 Affects the Hair-Inductive Capacity of Three-Dimensional Cultured Dermal Papilla Cells
CCL5 is important for the hair growth potential of human dermal papilla cells.
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research CXCL12 Neutralizing Antibody Promotes Hair Growth in Androgenic Alopecia and Alopecia Areata
Blocking the protein CXCL12 with a specific antibody can increase hair growth in common hair loss conditions.
research CXCL12 Inhibits Hair Growth Through CXCR4
CXCL12 protein slows down hair growth through its receptor CXCR4. Blocking this can potentially increase hair growth.
research Anti-CXCL4 Monoclonal Antibody Accelerates Telogen to Anagen Transition and Attenuates Apoptosis of the Hair Follicle in Mice
The anti-CXCL4 antibody helps mice grow hair faster and prevents hair loss.
research Rapid Skin Repigmentation on Oral Ruxolitinib in a Patient with Coexistent Vitiligo and Alopecia Areata
A man with vitiligo and alopecia saw quick skin and hair improvement with ruxolitinib, but skin color gains were lost after stopping treatment.
research Treatment of an Alopecia Areata Patient with Tofacitinib Results in Regrowth of Hair and Changes in Serum and Skin Biomarkers
A patient with alopecia areata regrew hair after taking tofacitinib and showed changes in certain blood and skin markers.
research CXCR3 Blockade Inhibits T Cell Migration Into the Skin and Prevents Development of Alopecia Areata
Blocking the CXCR3 receptor reduces T cell accumulation in the skin and prevents hair loss in mice.
research Identification of Ectodysplasin Target Genes Reveals the Involvement of Chemokines in Hair Development
Chemokine signaling is important for hair development.
research Abnormal Epigenetic Modifications in Peripheral Blood Mononuclear Cells from Patients with Alopecia Areata
Epigenetic changes in blood cells may contribute to alopecia areata.
research Reconstructed Human Skin Shows Epidermal Invagination Towards Integrated Neopapillae Indicating Early Hair Follicle Formation In Vitro
The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.
research Inhibition of Inflammatory Gene Expression in Keratinocytes Using a Composition Containing Carnitine, Thioctic Acid, and Saw Palmetto Extract
The composition with carnitine, thioctic acid, and saw palmetto extract may effectively reduce inflammation in hair follicle cells.
research Antroquinonol Exerts Immunosuppressive Effect on CD8+ T Cell Proliferation and Activation to Resist Depigmentation Induced by H2O2
Antroquinonol may help prevent skin depigmentation by suppressing certain immune cells.
research Exploring Mast Cell–CD8 T Cell Interactions in Inflammatory Skin Diseases
Mast cells and CD8 T cells interact closely in skin diseases, affecting each other's behavior and contributing to conditions like psoriasis and eczema.
research Candidate Gene Analysis of Alopecia Areata in Jordanian Population of Arab Descent: A Case-Control Study
The study found that a specific genetic variation in the TNFα gene is significantly linked to Alopecia Areata in the Jordanian Arab population.
research Emerging Role of Dermal White Adipose Tissue in Modulating Hair Follicle Development During Aging
Fat tissue under the skin affects hair growth and aging; reducing its inflammation may help treat hair loss.
research Single-Cell Sequencing Reveals Differential Cell Types in Skin Tissues of Liaoning Cashmere Goats and Key Genes Potentially Related to the Fineness of Cashmere Fiber
Certain genes are linked to the quality of cashmere in goats.
research Future Directions in the Treatment of Vitiligo
New treatments for vitiligo may focus on protecting melanocyte stem cells from stress and targeting specific pathways involved in the condition.
research Molecular Profiling of Frontal Fibrosing Alopecia Reveals TH1 and JAK-STAT Up-Regulation with No Suppression of Hair Keratins
Frontal fibrosing alopecia shows increased inflammation and JAK-STAT pathway activity without reduced hair proteins.
research 10× Genomics Single-Cell Sequencing Reveals Differential Cell Types in Skin Tissues of Liaoning Cashmere Goats and Key Genes Potentially Related to the Fineness of Cashmere Fiber
The study found specific skin cells and genes that may affect the quality of cashmere in Liaoning Cashmere Goats.
research Neutrophils Promote CXCR3-Dependent Itch in the Development of Atopic Dermatitis
Neutrophils are important for causing chronic itch in atopic dermatitis, and blocking the CXCR3 receptor may reduce this itch.
research Pathogenesis of Alopecia Areata and Vitiligo: Commonalities and Differences
Alopecia areata and vitiligo share immune system dysfunction but differ in specific immune responses and affected areas.
research Elevation of Circulating DNAs of Disease-Associated Cytokines in Serum Cell-Free DNA from Patients with Alopecia Areata
Higher levels of certain DNAs in blood may indicate hair follicle damage in alopecia areata patients.
research AP-2α/AP-2β Transcription Factors Are Key Regulators of Epidermal Homeostasis
AP-2α and AP-2β are crucial for healthy skin and hair.
research AP-2α/AP-2β Transcription Factors Are Key Regulators of Epidermal Homeostasis
AP-2α and AP-2β proteins are essential for healthy adult skin and hair.
research IKZF1 and IKAROS Overexpression Contributes to the Pathogenesis of Alopecia Areata
Too much IKZF1 and Ikaros protein may cause alopecia areata.
research Dynamic and Spatial Transcriptional Responses in COVID-19-Related Chilblains
COVID-toes show a unique immune response over time, different from vaccine-related chilblains.
research Pre-Clinical In-Vitro Assays for High Throughput Screening of Drug Candidates for Protection and Restoration of Immune Privilege in Alopecia Areata
The research developed methods to test drugs that could protect and restore hair follicle protection in a hair loss condition.
research Chronic Graft-Versus-Host Disease Exhibits Distinct Th1-Skewing and Barrier Abnormalities in the Skin
Chronic graft-versus-host disease in the skin shows strong Th1 immune response and unique barrier issues.
research Integrating Single-Cell and Spatial Transcriptomics of Human Hair Follicles to Define Transcriptional Signature of Follicular Dermal Papilla
The research identified specific genes that are active in the cells crucial for hair growth.
research Anti-Ku Antibodies: Much More Than Scleromyositis
Patients with Systemic Sclerosis have much higher levels of GDF-15, which could help predict organ involvement and guide treatment.