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In this clinical study, the use of potentiated zinc pyrithione shampoo improved scalp health and hair surface characteristics, suggesting that unhealthy scalp conditions may negatively impact pre-emergent hair's cuticle surface.

This study found that extensive cuticle damage from diperisophthalic acid oxidation did not alter the tensile properties of human hair, suggesting that these properties are mainly due to the cortex rather than the cuticle.

This study found that disrupting the Sox21 gene in mice led to progressive hair loss and regrowth, identifying Sox21 as a key regulator of hair shaft cuticle differentiation.

This study found that repeated exposure to ozonated water caused oxidative changes in hair proteins, lipids, and pigments, leading to altered hair properties, with minimal effects on shine and color.

This study found that selected polymeric pretreatments on hair can significantly reduce breakage and protect against thermal damage from hot flat irons by maintaining cuticle integrity and moisture.

The study found that a polymer treatment changes the charge on hair surfaces, making bleached hair smoother and less porous.

This study reported that a bioderived melanoidin/tannic acid nanocomplex forms a durable, antioxidant-active coating on hair fibers, providing enhanced UV protection and improving tensile resilience by suppressing oxidative stress and activating endogenous antioxidant pathways.

This study found that biotinoyl tripeptide-1-loaded solid lipid nanoparticles significantly improved thermal protection in hair, enhancing cuticle integrity and resistance to heat damage, compared to control samples.

In this study, BTP-loaded solid lipid nanoparticles were developed and shown to protect hair from heat-induced damage by enhancing cuticle integrity and thermal resistance in simulated thermal straightening conditions.

This study demonstrates that a newly developed bio-based, dual-phasic hair serum offers a sustainable and effective alternative to traditional silicone-based serums, enhancing hair cuticle integrity and consumer appeal while supporting environmentally friendly formulation design.

In this study, researchers addressed the limitations of adenosine's practical application in treating inflammation, oxidative stress, and tissue repair due to its poor water solubility and low transdermal permeability. Results are not reported in the abstract.

This study found that using 369LAB Lipid Bond, derived from plant oil triglycerides, can restore lipid content in damaged hair to natural levels and improve hair strength, integrity, and resilience after a single application, with benefits persisting even after discontinuation.

This study tested the effects of protective pre-treatments on African hair and found that these treatments, combined with moderate grooming, may help maintain cuticle integrity.

This study demonstrates that spatially resolved IR and Raman imaging can effectively reveal the molecular structure and composition of untreated human hair, providing insights into its chemistry and structural integrity.

Hair styling products can damage hair over time.

This study identified a novel keratin-associated protein, KAP24.1, which is specifically expressed in the human scalp and located in the hair cuticle.

This study suggests that TGase 3 may contribute to hair fiber scaffolding by forming specific isopeptide bonds between keratin intermediate filaments and keratin-associated proteins.

In this study, researchers using a UVB-induced mouse model identified the gene COL7A1 as a novel marker for hair luster, finding that minoxidil, caffeine, and biotin effectively restored its expression, indicating potential therapeutic strategies.

This study identified KRT82 as a significant Alopecia Areata risk gene, finding that rare damaging variants are linked to elevated immune cell infiltration around hair follicles in affected individuals.

This study found that rare damaging variants in the KRT82 gene, which affect hair shaft integrity, may contribute to the risk of alopecia areata.

This in-vitro study reported that a luliconazole-based formulation improved hair cuticle integrity and was more effective than ketoconazole in repairing damaged hair after 5 and 10 washes, with sensory analysis supporting these results. Further human studies are needed to confirm its clinical effects.

This article discusses how drug molecules integrate into hair fibers, focusing on biological transport mechanisms and physicochemical factors, but reports no new experimental findings.

In this study, researchers found that UV radiation causes hydroxy radicals to form cuticle holes specifically between the cuticle layers in wet hair, unlike random holes caused by Fenton's reaction.

This study investigated the effects of intensive hair dye use in mixed-breed dogs and found changes in the cuticle of the hair shaft and the epidermis using scanning electron microscopy.

This study found that exposure to Prussian Blue caused significant detachment of cuticle segments from the hair shaft in both new and aged human hairs.

This study observed that treating human hair with NaOH led to partially removed cuticles, resulting in better fiber cohesion and mechanical properties similar to wool, unlike bleach or formic acid treatments, which weakened the fibers.

Pollution exposure speeds up hair damage.

This study found that peroxide-rich plasma-activated water caused minimal morphological damage to hair, while nitrate-rich plasma-activated water induced significant damage, especially in porous hair types.

This review examines the pH levels of various shampoos and reports no new clinical results, highlighting the potential importance of labeling pH values on shampoo packaging for hair and scalp health.

This study found that keratin essence effectively protected hair structure against dye-induced damage, potentially improving coloring efficiency in damaged hair observed from a single individual.