27 citations
,
May 2019 in “Cosmetics” This review explores the structure and development of the hair cuticle, highlighting difficulties in studying some aspects and proposing new experimental approaches, but reports no new clinical results.
17 citations
,
February 1987 in “Journal of the American Academy of Dermatology” This study observed that daily selenium sulfide shampoos successfully removed fungal spores hidden beneath the hair cuticle in patients infected with ectothrix Microsporum canis.
3 citations
,
March 2009 in “Hirosaki University Repository for Academic Resources (Hirosaki University)” This study in hairless rats suggests that the deletion of specific hair keratin genes contributes to hypotrichosis and highlights the strain's potential as a model for hair follicle research.
1 citations
,
January 2018 in “Journal of microscopy and ultrastructure” In this study, researchers used SEM/SDD-EDS to identify waterborne minerals like calcium and aluminum in the scalp hair cuticle of individuals using treated or untreated water for hair washing, finding that prior application of coconut oil or conditioners can prevent calcium uptake.
1 citations
,
November 2003 in “Humana Press eBooks” This article discusses the use of atomic force microscopy for examining human hair surfaces in dermatology, cosmetics, and forensic science, but presents no new research findings.
January 2025 in “Journal of Raman Spectroscopy” This study observed that the Raman spectra of human hair cuticle vary with polarization and direction of signal collection, identifying certain spectral bands as markers sensitive to the structural changes in keratin secondary and tertiary structures.
May 2024 in “Indian journal of pharmacy and pharmacology” This in-vitro study reported that a luliconazole-based formulation improved hair cuticle integrity and was more effective than ketoconazole in repairing damaged hair after 5 and 10 washes, with sensory analysis supporting these results. Further human studies are needed to confirm its clinical effects.
January 2024 in “Uttar Pradesh journal of zoology” In this study, researchers found that chemical treatments like bleaching can cause severe damage to the hair cuticle, with previously modified hair showing complete deterioration compared to the partial degradation seen in virgin hair, highlighting the need for mindful cosmetic practices.
May 2017 in “Journal of microscopy and ultrastructure” This notice states that the article has been withdrawn due to the journal's transfer to a new publisher and reports no research findings.
This study found that exposure to Prussian Blue caused significant detachment of cuticle segments from the hair shaft in both new and aged human hairs.
This study found considerable variation in hair shaft proteomic profiles among Caucasian, African-American, Kenyan, and Korean subjects, with individual and site-specific differences observed.
This study used proteomic profiling to reveal significant individual and site-specific differences in human hair shaft proteins, which may improve the differentiation of hair based on ethnic origin and individual identity.
73 citations
,
May 2009 in “Proceedings of the National Academy of Sciences” This study found that disrupting the Sox21 gene in mice led to progressive hair loss and regrowth, identifying Sox21 as a key regulator of hair shaft cuticle differentiation.
12 citations
,
January 1988 in “YAKUGAKU ZASSHI” This study found that Polygonum multiflorum and Panax japonicum extracts could promote hair regrowth in mice, suggesting potential use as hair tonics.
11 citations
,
May 2013 in “Journal of Investigative Dermatology” KRTAP10 proteins help form the hair shaft's tough outer layer by interacting with specific hair keratins.
1 citations
,
January 1992 in “DNA sequence” This study found that a cuticle keratin gene in sheep is a pseudogene due to gene duplication and mutations, lacking expression in vivo.
10 citations
,
March 2005 in “International Journal of Cosmetic Science” This study found that photochemical and cosmetic chemical oxidation of hair causes surface damage by delipidation and acid formation, which can be characterized and quantified using microfluorometry and X-ray photoelectron spectroscopy.
February 2020 in “The Pharmaceutical Society of Japan” 15 citations
,
January 1991 in “Mammalian Genome” 6 citations
,
April 2005 in “Journal of dermatological science” This study identified the expression sites of five KAP5 genes on human chromosome 11q13.5 in scalp skin sections but did not explore their detailed distribution within hair follicles.
35 citations
,
September 1994 in “Journal of Investigative Dermatology”
17 citations
,
December 2002 in “Biochemical and biophysical research communications” This study reports on the biochemical characteristics of S100A3 protein in human hair cuticle, notably finding its N-terminal methionine is acetylated and has a slightly lower isoelectric point compared to the recombinant version.
November 2022 in “International journal of trichology” This study found that glyoxylic acid caused more protein loss in hair compared to traditional alkaline straighteners, though both types of treatments showed comparable effects on hair tensile strength.
January 2008 in “Medical Entomology and Zoology” 248 citations
,
April 1988 in “Differentiation” In this study, researchers observed that trichocytic and epithelial cytokeratins have distinct expression patterns within various human and bovine hair follicle cells, contributing to understanding hair follicle development and growth.
161 citations
,
July 2003 in “ACM Transactions on Graphics” In this study, a new shading model for hair was developed that better matches real-life light scattering, thanks to detailed new measurements of hair fiber scattering not predicted by existing models.
117 citations
,
August 2005 in “Ultramicroscopy” This study systematically characterized the nanomechanical properties of human hair, such as hardness and elastic modulus, across different ethnicities and treatment conditions using nanoindentation and scanning electron microscopy.
109 citations
,
June 2000 in “Development” This study reports that activating Notch signaling in the hair follicle cortex of transgenic mice caused abnormal differentiation of the medulla and cuticle, highlighting potential cell-cell interactions.
98 citations
,
December 1991 in “Annals of the New York Academy of Sciences” This study found that conserved DNA motifs and expression patterns in keratin genes suggest functional regulatory similarities in hair follicle differentiation across different mammalian species.
This study introduced a new hair shading model that more accurately simulates light scattering on hair fibers, capturing effects not predicted by previous models.