Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This document includes a brief professional profile of Dr. Ralf Paus but presents no research findings or study results.

This review reports on the effects of aging on hair characteristics such as pigmentation, growth, and structural properties across genders and ethnicities, highlighting the importance of scalp health and suggesting cosmetic solutions to improve the appearance of aged hair.

This review discusses the roles and mechanisms of glycosaminoglycans in wound healing and presents challenges and potential applications for GAG-based biomaterials without reporting new experimental results.

This study suggests that some keratin-associated proteins with antecedents found in non-haired animals may have roles beyond hair characteristics, possibly contributing to the evolution of hair follicles.

This study analyzed the genetics of the patchiness phenotype in New Zealand rabbits and found that the gene KRT82, with identified SNPs in its promoter, may serve as a potential biomarker for breeding these rabbits.

This review discusses the evolution and potential of non-invasive imaging techniques for diagnosing scalp diseases, highlighting their advantages and limitations compared to trichoscopy and scalp biopsy, the current diagnostic standards.

In this study, a modified Xception deep learning model achieved a 92% accuracy rate in diagnosing hair and scalp disorders, significantly outperforming other models, suggesting AI could improve dermatological diagnostics' accuracy and accessibility.

This study explored using keratin extracted from human hair waste to create biodegradable bioplastic films, revealing promising potential for applications in packaging and disposable items due to their uniform surface morphology and ability to degrade with keratinophilic fungi.

In this study, researchers found that deleting Med1, a key epigenetic regulator in dental epithelia, led to hair growth on mouse incisors by altering enhancer landscapes and causing a switch from dental to hair lineage transcription programs.

This study suggests that UVA-responsive nanocapsules may provide an effective method for skin antisepsis by releasing ethanol and reducing microorganisms within hair follicles on ex vivo porcine ear skin.

This study observed that activating the Wnt/β-catenin pathway enhances hair follicle stem cell proliferation and differentiation, promoting hair growth and wound healing, and demonstrated the potential for outer root sheath transplants to aid skin repair, although challenges remain for clinical application.

This review found that exposure to pollutants like PM, NOx, and PAHs is linked to various skin and hair disorders, indicating a need for cosmetics with natural adsorbents to reduce pollutant effects, achieving 30-55% removal efficiency.

The researchers reported finding a recessive nonsense variant in the EGFR gene responsible for perinatal lethality in the "Blonde d'Aquitaine" cattle breed, prompting the development of a screening test to help eradicate this genetic flaw.

This review highlighted recent advances in nanocarrier-based topical delivery systems for skincare, emphasizing their potential to enhance ingredient stability, penetration, and targeted release while addressing specific pathophysiological skin concerns.

This study identified nine pathogenic variants in the PADI3 gene and variants in the S100A3 and TCHH genes in patients with central centrifugal cicatricial alopecia, suggesting a broader genetic basis for the disease and potential targets for genetic testing and therapies.

This review explores the role of FGF signaling in hair follicle development and highlights its potential as a new therapeutic target for hair loss, which could surpass existing treatments in terms of efficacy and safety.

In this study, chitosan nanoparticles loaded with phenobarbital were the most effective in promoting hair regrowth and quality in a mouse model of chemotherapy-induced alopecia, suggesting potential for preventing hair loss in cancer patients.

In this study, researchers observed significant differences in hair follicle microbiome diversity and microbial composition between hair loss and healthy groups, uncovering specific patterns and functional changes associated with female pattern hair loss, which may aid future targeted approaches for androgenetic alopecia.

This study found that treating hair with ATS, formed from fumaric acid and cysteamine, effectively improved hair quality by increasing moisture content and altering the internal structure of strong curls.

In this study using a mouse model, RIPK1 inhibitors were found to delay the onset of alopecia areata, reduce immune cell numbers in affected skin, and increase hair length, indicating a potential therapeutic role in preventing alopecia areata.

In this study, researchers identified thousands of mRNA, lncRNA, circRNA, and miRNA transcripts involved in different hair follicle stages of Rex rabbits and highlighted significant gene expression changes and pathway enrichments, providing insights into the regulatory mechanisms of hair development in these animals.

This study examined the role of long non-coding RNAs in wool fineness among Gansu alpine fine-wool sheep, identifying specific lncRNAs and target genes that may enhance wool quality.

In this study, reducing agents like ammonium thioglycolate, L-cysteine, and sodium sulfite in shampoo effectively decreased hair flyaway and frizz without causing damage, as no critical hair damage was observed in structural and tensile strength assessments.

This research highlights the essential role of skin findings in diagnosing and managing rheumatic diseases, emphasizing their importance in early recognition, classification, and treatment planning, which requires collaboration between rheumatologists and dermatologists.

In this study, researchers conducted whole-genome resequencing of eight sheep breeds to identify additional genes associated with wool fineness, revealing 269 genes in fine wool and 319 in coarse wool breeds that are linked to significant traits and pathways.

This study found that using a microfiber towel to dry human hair better preserves hair keratin integrity and wear resistance compared to blow-drying or using a cotton towel, as indicated by stronger alpha-helix structure in FTIR analysis.

This study suggests that specific genetic changes, including mutations in protein-coding genes and noncoding regions, have contributed to the evolution of hairlessness in multiple mammalian species.

This study provides genomic and epigenomic insights into the white wax scale insect, highlighting high methylation levels and differential hormone profiles linked to its sexual dimorphism and developmental differences.

This study reported discovering a novel missense variant in a case of autosomal recessive woolly hair in a 31-year-old Chinese woman, which significantly reduced secretion of the encoded protein, likely leading to disease by impairing its hydrolytic function.

This study found that CRISPR/Cas9-induced loss-of-function mutations in the FGF5 gene significantly increased wool length and yield in genetically modified Chinese Merino sheep compared to wild-type controls.