research TRP Channels in Skin Biology and Pathophysiology
TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
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research Analysis of Hidradenitis Suppurativa-Linked Mutations in Four Genes and the Effects of PSEN1-P242LfsX11 on Cytokine and Chemokine Expression in Macrophages
The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.
research The Wound Microbiome
The document concludes that better understanding the wound microbiome can improve chronic wound care by preserving helpful bacteria and targeting harmful ones.
research Diverse Cellular Players Orchestrate Regeneration After Wounding
Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.
research mTORC1 Activity Controls Human Scalp Hair Follicle Pigmentation and Growth
mTORC1 activity is important for hair growth and color, and targeting it could help treat hair loss and greying.
research Adipose Mesenchymal Stromal Cell-Derived Exosomes Carrying MiR-122-5p Antagonize the Inhibitory Effect of Dihydrotestosterone on Hair Follicles by Targeting the TGF-β1/SMAD3 Signaling Pathway
ADSC-Exos with miR-122-5p can help treat hair loss by promoting hair growth.
research The Role of Lymphocytes in the Development and Treatment of Alopecia Areata
Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.
research Ornithine Decarboxylase as a Target for Chemoprevention of Basal and Squamous Cell Carcinomas in Ptch1+/– Mice
Targeting ornithine decarboxylase can help prevent skin cancer.
research Skin Manifestations of Targeted Antineoplastic Therapy
Cancer treatments targeting specific cells often cause skin problems, which can affect how much medicine patients can take.
research Calreticulin: Non-Endoplasmic Reticulum Functions in Physiology and Disease
Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.
research Regulatory T Cells in Inflammatory Skin Disease: From Mice to Humans
Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.
research Fatal Toxic Epidermal Necrolysis Associated With Cetuximab in a Patient With Colon Cancer
A cancer patient died from a severe skin reaction after taking the drug cetuximab.
research Tofacitinib Citrate Alleviates Alopecia Universalis Symptoms in Recent Case Study
Tofacitinib helped a person with total body hair loss grow hair again without bad side effects.
research Immunology and Genetics
The document concludes that Borrelia afzelii causes a skin condition in France, a gene is linked to hair loss in Caucasian women, and various genetic mutations affect skin diseases.
research Cancer
Some medications can improve skin conditions, while lifestyle factors like smoking and drinking may worsen them; treatments like monoclonal antibodies and imiquimod cream show promise for certain skin diseases.
research Internal Medicine: Retrospective Review of 120 Patients Over a 10-Year Period
Certain drugs can cause skin lupus, but stopping the drug usually helps. Vaccines work against smallpox, genital herpes, and a type of human papillomavirus. More frequent light therapy clears psoriasis faster. Certain treatments work for psoriasis and dermatitis. A specific cream effectively treats a type of skin cancer. Low iron levels aren't directly linked to chronic hair loss.
research Stem Cells in Skin Regeneration, Wound Healing, and Their Clinical Applications
Stem cells are crucial for skin repair and new treatments for chronic wounds.
research Transfollicular Drug Delivery: Is It a Reality?
Hair follicles may soon be used more for targeted and systemic drug delivery.
research Diagnosis and Management of the Dermatologic Manifestations of Polycystic Ovary Syndrome
The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.
research Stem Cell Quiescence Acts as a Tumor Suppressor in Squamous Tumors
Inactive hair follicle stem cells help prevent skin cancer.
research Epidermal Stem Cells: Practical Perspectives and Potential Uses
Epidermal stem cells could lead to new treatments for skin and hair disorders.
research Review Article: Dermatological Complications of Immunosuppressive and Anti-TNF Therapy in Inflammatory Bowel Disease
Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.
research Treatment of Generalized Lichen Planus With Alefacept
Alefacept may effectively treat severe lichen planus, with patients showing significant improvement and no side effects.
research The Role of Adipocytes in Tissue Regeneration and Stem Cell Niches
Fat cells are important for tissue repair and stem cell support in various body parts.
research Macroenvironmental Regulation of Hair Cycling and Collective Regenerative Behavior
Hair growth is influenced by various body and external factors, and neighboring hairs communicate to synchronize regeneration.
research The Influence of Interferon on Healthy and Diseased Skin
Type I interferons play a key role in the development of various skin diseases.
research Eyebrow Loss
Eyebrow loss has many causes and requires accurate diagnosis for proper treatment.
research Interferons in Dermatology
Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.
research Chemotherapy-Induced Iatrogenic Injury of Skin: New Drugs and New Concepts
New chemotherapy drugs cause skin side effects, but treatments like minocycline and tetracycline can help reduce them.
research Multiple Roles of Integrin-Linked Kinase in Epidermal Development, Maturation, and Pigmentation Revealed by Molecular Profiling
ILK is essential for skin development, pigmentation, and healing.