research Keratin-6 Driven ODC Expression in Hair Follicle Keratinocytes Enhances Stemness and Tumorigenesis by Negatively Regulating Notch
ODC overexpression in hair cells increases tumor growth by reducing Notch signaling.
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research Cell-Based Model Systems for Validation of Efficacy Claims for Cosmetic Ingredients
Cell-based models help test if cosmetic ingredients really work for hair growth and skin health.
research GDNF Promotes Hair Formation and Cutaneous Wound Healing by Targeting Bulge Stem Cells
GDNF helps grow hair and heal skin wounds by acting on hair stem cells.
research Polymeric Micelle Mediated Follicular Delivery of Spironolactone: Targeting the Mineralocorticoid Receptor to Prevent Glucocorticoid-Induced Activation and Delayed Cutaneous Wound Healing
Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.
research Faculty Opinions Recommendation of GDNF Promotes Hair Formation and Cutaneous Wound Healing by Targeting Bulge Stem Cells
GDNF helps grow hair and heal skin wounds by acting on specific stem cells.
research Epidermal Growth Factor Receptor Inhibitors: A Review of Cutaneous Adverse Events and Management
Skin side effects from cancer drugs targeting EGFR can affect treatment adherence but can be managed with antibiotics like tetracycline.
research Acanthosis Nigricans, Insulin Resistance, And Cutaneous Virilism
Patients with acanthosis nigricans often have insulin resistance and signs of increased male hormones, but treatment targeting these male hormones is generally ineffective.
research Cutaneous Drug Delivery: An Update
New methods like nanoparticles and microneedles show promise for better skin drug delivery, especially for hair disorders.
research Incidence and Management of Cutaneous Toxicities Associated with Cetuximab
Cetuximab often causes skin rashes, and managing these is important for cancer treatment.
research Cutaneous Adverse Effects of Targeted Therapies
Targeted cancer therapies often cause skin side effects, needing dermatologist care.
research Cutaneous Adverse Effects of Targeted Therapies
Targeted cancer therapies often cause serious skin problems that need careful management.
research Cutaneous Scarring: Basic Science, Current Treatments, and Future Directions
New effective scar treatments are urgently needed due to the current options' limited success.
research Novel Micelle Formulations to Increase Cutaneous Bioavailability of Azole Antifungals
New micelle solutions greatly improve skin delivery of certain antifungal drugs.
research Epidermal PPARγ Is a Key Homeostatic Regulator of Cutaneous Inflammation and Barrier Function in Mouse Skin
PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.
research Laser-Assisted Drug Delivery for the Treatment of Androgenetic Alopecia: Ablative Laser Fractional Photothermolysis to Enhance Cutaneous Topical Delivery of Platelet-Rich Plasma — With or Without Concurrent Bimatoprost and/or Minoxidil
Laser-assisted delivery of PRP, with or without bimatoprost and minoxidil, can effectively stimulate hair growth.
research Basic Concepts, Current Evidence, And Future Potential For Gene Therapy In Managing Cutaneous Wounds
Gene therapy shows promise for improving wound healing, but more research is needed for human use.
research Cutaneous Manifestations of Polycystic Ovary Syndrome
Skin problems in PCOS, like excess hair, acne, and hair loss, may not always indicate high male hormone levels and need careful diagnosis for proper treatment.
research Cutaneous Microbial Biofilm Formation as an Underlying Cause of Red Scrotum Syndrome
Microbial biofilms may cause red scrotum syndrome.
research Cutaneous Distribution of Orally Administered Itraconazole in Guinea Pigs Studied by Autoradiography
Oral itraconazole effectively reaches and treats deep skin layers in guinea pigs.
research Dyad of Infantile Cutaneous and Thymic Langerhans Cell Histiocytosis: Is It Rare?
Thymic LCH may be underdiagnosed, so thymic ultrasound should be considered in infants with cutaneous LCH.
research Conventional Histopathology and New Technologies in Cutaneous Mucinoses: Old Diagnostic Criteria and New Therapeutic Perspectives
New technologies show potential for better understanding and treating skin conditions with abnormal mucin, but more research is needed for clinical use.
research Calcineurin/Nuclear Factor of Activated T-Cell Pathway in Cutaneous Squamous Cell Carcinoma
The calcineurin/NFAT pathway plays a significant role in the development and growth of a type of skin cancer called cutaneous squamous cell carcinoma.
research Cutaneous T-Cell Lymphoma
The document concludes that DAB389-IL2 is promising for treating refractory cutaneous T-cell lymphoma, but more research is needed on its effectiveness and side effect management.
research Cutaneous Lupus Erythematosus: Overview and Treatment
The document concludes that Cutaneous Lupus Erythematosus has different forms, is influenced by genetic and environmental factors, and can be treated with various medications, but more targeted therapies are needed.
research Perspectives in Dermatopathology: Telomeres and Telomerase in Aging and Cancer with Emphasis on Cutaneous Disease
Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.
research Pathology and Pathogenesis of Cutaneous Lesions in Beef Cattle Associated with Buffalo Fly Infestation
Buffalo flies and Stephanofilaria nematodes cause severe skin lesions in beef cattle, and treatment should target both.
research Alopecia Areata Exhibits Cutaneous And Systemic OX40 Activation Across Atopic Backgrounds
Alopecia areata patients show increased inflammation and OX40 activation, suggesting a new treatment target.
research Mechanisms of Cutaneous Adverse Events During Targeted Cancer Therapy
Targeted cancer therapies can cause skin side effects, but activating SOS in the skin may help reduce them.
research Symptom Impact and Unmet Need in Systemic/Cutaneous Lupus Erythematosus: Results from a Patient-Centered Study Set in a Social Media Community
SLE significantly affects daily life, especially through fatigue and joint pain, highlighting the need for better treatments.
research The Role of Androgen and Androgen Receptor in Skin-Related Disorders
Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.