research TRPA1 Modulates Mechanotransduction in Cutaneous Sensory Neurons
TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.
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research Bacteria Induce Skin Regeneration via IL-1β Signaling
Bacteria can help skin regenerate through a process called IL-1β signaling.
research Diversification and Specialization of Touch Receptors in Skin
Skin has specialized touch receptors that can tell different sensations apart.
research The Functional Organization of Cutaneous Low-Threshold Mechanosensory Neurons
Different hair follicles in the skin are innervated by unique combinations of mechanosensory neurons, crucial for touch sensation.
research Oxytocin Receptor Is Present in Keratinocytes Near Touch and Pain Sensory Neurons
Oxytocin receptors are found in skin cells near touch and pain neurons.
research ELife Assessment: Touch Receptor End-Organ Innervation and Function Require Sensory Neuron Expression of the Transcription Factor Meis2
Meis2 is essential for touch sensation and proper nerve connection to touch receptors in certain skin areas of mice.
research TRP Channels in Skin Biology and Pathophysiology
TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
research Neurobiology, Stem Cell Biology, and Immunology: An Emerging Triad for Understanding Tissue Homeostasis and Repair
The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.
research KCNQ Potassium Channels Modulate Sensitivity of Skin Down-Hair (D-Hair) Mechanoreceptors
KCNQ potassium channels help control the sensitivity of touch receptors in the skin.
research Sensitive Skin
Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.
research A Subpopulation of Itch-Sensing Neurons Marked by Ret and Somatostatin Expression
Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.
research Follicle-Innervating Aδ-Low Threshold Mechanoreceptors Organize Through a Population-Dependent Mechanism
Mouse touch-sensitive nerve cells adjust their connections based on competition with other similar cells.
research Concise Review: Tissue-Engineered Skin and Nerve Regeneration in Burn Treatment
New methods for skin and nerve regeneration can improve healing and feeling after burns.
research Touch Receptors Undergo Rapid Remodeling in Healthy Skin
Touch sensitivity in mouse skin decreases during hair growth due to changes in touch receptors.
research The Cellular Basis of Mechanosensory Merkel-Cell Innervation During Development
BMP signaling is essential for the development of touch domes.
research Symmetry Breaking of Tissue Mechanics in Wound-Induced Hair Follicle Regeneration
Activating TRPA1 reduces scarring and promotes tissue regeneration.
research Neuronal Plasticity of the Brain-Skin Connection: Stress-Triggered Up-Regulation of Neuropeptides in Dorsal Root Ganglia and Skin via Nerve Growth Factor-Dependent Pathways
Stress increases certain chemicals in the skin and nerves, which might worsen skin conditions.
research The Murine Hair Follicle Is a Melatonin Target
Melatonin directly affects mouse hair follicles and may influence hair growth.
research Neurogenic Inflammation in Stress-Induced Termination of Murine Hair Growth Is Promoted by Nerve Growth Factor
Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.
research Neural Mechanisms of Hair Growth Control
Nerves and chemicals in the body can affect hair growth and loss.
research Neuroimaging of Sleep and Depression
Sleep problems and skin issues affect each other; poor sleep can worsen skin conditions, and some skin treatments can improve or harm sleep quality.
research A Hot New Twist to Hair Biology: The Role of TRPV1 in Human Hair Growth Control
Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.
research A Role for p75 Neurotrophin Receptor in the Control of Apoptosis-Driven Hair Follicle Regression
The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.
research The Endocannabinoid System of the Skin: A Potential Approach for the Treatment of Skin Disorders
Targeting the skin's endocannabinoid system could help treat skin disorders.
research Unmet Medical Needs in Chronic, Non-Communicable Inflammatory Skin Diseases
There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.
research Pruritus, Allergy and Autoimmunity: Paving the Way for an Integrated Understanding of Psychodermatological Diseases
The conclusion is that understanding the complex relationship between allergies, autoimmunity, and psychological factors is key to treating skin disorders with itching.
research Characterization of CD4+ Stem Cells of the Skin and Their Role in Skin Homeostasis and Tumorigenesis
CD4+ skin cells may be precursors to basal cell carcinoma.
research Iron Deficiency Anemia Pruritus: A Review with Proposed Mechanisms of Action
Iron deficiency anemia can cause itching, which often improves with iron supplements.
research The Human Skin as a Hormone Target and an Endocrine Gland
Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
research The Itchy Scalp: Scratching for an Explanation
Scalp itching is common and hard to diagnose due to the complex nerve structure of the scalp.