19 citations,
May 2021 in “Clinical, Cosmetic and Investigational Dermatology” Minoxidil and finasteride are the best for non-scarring hair loss; more research is needed for scarring hair loss treatments.
11 citations,
July 2018 in “AJGP” Low-dose oral minoxidil effectively reduces hair loss in women with female pattern hair loss.
3 citations,
October 2023 in “Military Medical Research/Military medical research” Regulatory T cells help heal skin and grow hair, and their absence can lead to healing issues and hair loss.
2 citations,
November 2022 in “JAAD case reports” COVID-19 vaccines may rarely worsen hair loss in people with severe alopecia, but the benefits of vaccination still outweigh this risk.
1 citations,
July 2023 in “Cancers” Skin side effects from CDK4/6 inhibitors in breast cancer patients are generally mild and treatable, allowing most patients to continue treatment.
January 2024 in “Journal der Deutschen Dermatologischen Gesellschaft” Non-biologic immunosuppressive drugs are crucial for treating autoimmune and chronic inflammatory skin diseases.
August 2023 in “Journal of the American Academy of Dermatology” A scalp biopsy is essential for accurately identifying different types of hair loss.
January 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Papulopustular rosacea is an inflammatory skin condition treatable with lifestyle changes and medications.
July 2019 in “Journal of Investigative Dermatology” The research found that male pattern hair loss is mostly genetic and involves hair thinning due to hormonal effects and changes in gene expression.
17 citations,
January 2015 in “International Journal of Trichology” Frontal fibrosing alopecia may affect nails and could be a type of lichen planus, treatable with certain medications.
6 citations,
September 2012 in “Our Dermatology Online” Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.
5 citations,
November 2021 in “Skin appendage disorders” Hair loss can cause stress and mental health issues, so treatments should address both the physical and psychological aspects, involving a team of dermatologists, psychologists, and hair specialists.
4 citations,
June 2021 in “Frontiers in Pharmacology” Bone marrow stem cells and their medium help hair regrowth.
1 citations,
January 2017 in “Current Dermatology Reports” Early baldness in men may indicate risks for obesity, metabolic syndrome, insulin resistance, and heart disease, similar to women with PCOS. Alopecia areata is often linked with autoimmune diseases and mental health issues. Certain hair disorders are due to genetic issues, and chemotherapy can cause hair loss through specific biological pathways. Iron deficiency's link to hair loss is still disputed.
426 citations,
August 2014 in “Nature Medicine” Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.
88 citations,
August 2019 in “Frontiers in immunology” Tyrosine kinases are important in skin autoimmune diseases and could be targets for new treatments.
54 citations,
September 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” Vitamin A affects hair loss and immune response in alopecia areata.
48 citations,
May 2013 in “Canadian Medical Association Journal” Primary cicatricial alopecia, a rare disorder causing permanent hair loss, is hard to diagnose and treat, with treatments like anti-inflammatory drugs and steroids offering varied results and no guaranteed cure. Psychological support for patients is important, and future research should aim to identify causes of the condition.
42 citations,
August 2013 in “International Journal of Women's Health” Female pattern hair loss is caused by multiple factors and while treatments like topical minoxidil, hormone therapy, and low-level light therapy can help, none can fully cure it.
35 citations,
June 2012 in “PloS one” Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.
20 citations,
March 2021 in “Drug design, development and therapy” Topical immunotherapy can treat alopecia areata, but its effectiveness varies and the exact mechanism is unclear.
16 citations,
April 2021 in “Frontiers in Cell and Developmental Biology” New hair follicles could be created to treat hair loss.
9 citations,
January 2020 in “Skin appendage disorders” Hair loss from conditions like LPP and FFA can potentially be reversed with the right treatment.
9 citations,
January 2020 in “Postepy Dermatologii I Alergologii” Frontal fibrosing alopecia is a poorly understood condition with increasing cases and unclear treatment effectiveness.
8 citations,
July 2022 in “International Journal of Molecular Sciences” Skin cells release substances important for healing and fighting infection, and understanding these could improve skin disorder treatments.
6 citations,
January 2020 in “Postepy Dermatologii I Alergologii” Trichoscopy is useful for diagnosing hair-pulling disorder.
6 citations,
January 2018 in “International Journal of Trichology” A married couple both developed a rare type of hair loss, possibly due to shared environmental factors.
5 citations,
December 2021 in “Frontiers in Cell and Developmental Biology” Enzymes called PADIs play a key role in hair growth and loss.
4 citations,
January 2014 in “Indian journal of paediatric dermatology” Methotrexate is effective and well-tolerated in children for certain skin conditions but requires careful monitoring.
4 citations,
June 2012 in “Journal of Investigative Dermatology” The symposium concluded that a specific lipid might cause hair loss, inflammation is a key factor, and stem cells in bald scalps aren't working right, suggesting new treatment targets.