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Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Estrogen therapy can reduce skin aging but has cancer risks.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Cathepsin L is essential for normal hair growth and development.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

Cancer cells often have more copies of TERT and TERC genes, which helps them grow and could affect patient outcomes.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

Oxidative stress contributes to hair graying and loss as we age.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

Activating TRPV3 stops human hair growth.

Thymus transplantation successfully restored immune function in infants with FOXN1 deficiency.

Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

One minoxidil-sensitive potassium channel exists in human hair follicles.