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Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.

Research on the human skin microbiome has grown, focusing on skin health and diseases, with more studies needed on antibiotic resistance and AI applications.

Stem cell therapies could be a promising alternative for hair loss treatment, but more research is needed to understand their full potential and safety.

The ABCA4 gene protects hair follicle stem cells from toxic vitamin A byproducts.

MicroRNAs are crucial for skin development, regeneration, and disease treatment.

Targeting CXXC5 and GSK-3β may help treat male pattern baldness.

Fish collagen peptides can significantly promote hair growth.

Extracellular vesicles may effectively treat hair loss with minimal side effects.

Skin cells called dermal fibroblasts are important for skin growth, hair growth, and wound healing.

Type 3 Innate Lymphoid Cells help maintain skin health and balance, and are involved in skin diseases and healing.

Vitamin D made by the skin plays a role in immune defense and skin health, and more research is needed to understand its full effects.

Polydeoxyribonucleotide (PDRN) may help lighten skin and treat hyperpigmentation.

Aloe vera gel helps heal open wounds better than coconut oil.

Laser therapy improved surgical scar healing in dogs.

Low-Level Laser Therapy may help with flap survival and burn scar healing, but not with venous ulcers or hair loss, and more research is needed.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Human amniotic membrane helps heal skin wounds faster and with less scarring.

Skin lesions in Carney complex are likely caused by a specific group of skin cells that promote pigment production due to a genetic mutation.

Fzd2 is important for skin and hair development through various signaling ways.

Chemicals and stem cells combined have advanced regenerative medicine with few safety concerns, focusing on improving techniques and treatment effectiveness.

Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.

Injury changes how hair follicle stem cells behave, depending on the hair growth stage.

PRP helps skin regeneration but needs standardized testing for consistent results.

Oral mTOR inhibitors often cause skin and hair side effects but usually don't require stopping treatment.

Hydroxypinacolone retinoate is a potent anti-aging ingredient for skin that is more effective and less irritating than other forms of retinoids.

Targeting the HEDGEHOG-GLI1 pathway could help treat keloids.

Older hair follicle stem cells have a reduced ability to renew themselves, leading to more hair loss.

Both Th1 and Th2 immune responses are increased in alopecia areata, with Th2 response more strongly linked to how severe the disease is.

Topical tofacitinib is effective in promoting hair growth for non-scarring alopecia.

Mutations in the WNT10A gene can cause skin, hair, teeth, and other disorders, and may also affect other areas like kidney and cancer, with potential for targeted treatments.